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硼替佐米诱发肾移植受者浅表性血管炎:1例罕见病例

Bortezomib-Induced Superficial Vasculitis in a Kidney Transplant Recipient: A Rare Case.

作者信息

Balwani Manish, Pasari Amit, Gurjar Prasad, Sejpal Kapil, Bawankule Charulata, Tolani Priyanka, Dubey Shubham, Kashiv Pranjal, Bhawane Amol, Malde Sunny, Gupta Sushrut

机构信息

Department of Nephrology, Saraswati Kidney Care Center, Nagpur, IND.

Department of Nephrology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND.

出版信息

Cureus. 2024 Apr 22;16(4):e58743. doi: 10.7759/cureus.58743. eCollection 2024 Apr.

Abstract

Bortezomib is a frequently administered immunosuppressive agent in kidney transplantation. A 30-year-old male kidney transplant recipient developed an atypical reaction on the left hand in terms of spider-like extensions, indicating erythematous inflammation along the superficial veins after bortezomib intravenous administration. The inflammation spontaneously resolved after three weeks with a bortezomib dose reduction. Nephrologists must be familiar with the potential cutaneous bortezomib-induced adverse effects.

摘要

硼替佐米是肾移植中常用的免疫抑制剂。一名30岁男性肾移植受者在左手出现了非典型反应,表现为蜘蛛样条索状,提示静脉注射硼替佐米后浅表静脉出现红斑性炎症。炎症在硼替佐米剂量减少后三周内自行消退。肾病学家必须熟悉硼替佐米可能引起的皮肤不良反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/250b/11110920/4c6c5d853813/cureus-0016-00000058743-i01.jpg

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