Singh Sonia, Sharma Shiwangi
Institute of Pharmaceutical Research GLA University, 17km Stone, NH-2, Mathura-Delhi Road Mathura, Chaumuhan, Uttar Pradesh, 281406, India.
Tata Consultancy Services, Delhi NCR, India.
Comb Chem High Throughput Screen. 2025;28(8):1331-1344. doi: 10.2174/0113862073316439240515072946.
Lignans, a group of naturally occurring compounds abundant in various plant-based foods, are becoming increasingly popular due to their potential health benefits. The literature suggests that these bioactive substances can reduce the risk of certain types of cancer, such as postmenopausal colon and breast cancer. Moreover, the significance of lignans for improving cardiovascular health has been recognized, as studies have revealed a potential correlation between the intake of lignans and a decreased risk of cardiovascular disease. These complex molecules possess diverse bioactive capabilities, rendering them potential alternatives for preventing chronic diseases. Further research is needed to examine the mechanisms responsible for their beneficial outcomes. Recent research has emphasized the pharmacological properties of lignans as effective substances for human health. Incorporating foods rich in lignans into the diet may be a practical approach to enhancing protection against life-threatening ailments, such as cardiovascular diseases and malignancies.
木脂素是一类在各种植物性食物中大量天然存在的化合物,由于其潜在的健康益处而越来越受欢迎。文献表明,这些生物活性物质可以降低某些类型癌症的风险,如绝经后结肠癌和乳腺癌。此外,木脂素对改善心血管健康的重要性已得到认可,因为研究表明木脂素的摄入量与心血管疾病风险降低之间存在潜在关联。这些复杂分子具有多种生物活性能力,使其成为预防慢性病的潜在替代品。需要进一步研究以探究其产生有益效果的机制。最近的研究强调了木脂素作为对人类健康有效的物质的药理特性。将富含木脂素的食物纳入饮食可能是增强对危及生命的疾病(如心血管疾病和恶性肿瘤)的防护的一种切实可行的方法。