Hino Haruaki, Yasuhara Yuki, Nakahata Katsutoshi, Utsumi Takahiro, Maru Natsumi, Matsui Hiroshi, Taniguchi Yohei, Saito Tomohito, Tsuta Koji, Okada Hidetaka, Murakawa Tomohiro
Department of Thoracic Surgery, Kansai Medical University, 2-5-1 Shinmachi Hirakata, Osaka, 573-1191, Japan.
Department of Obstetrics and Gynecology, Kansai Medical University, Osaka, Japan.
Surg Case Rep. 2024 May 23;10(1):129. doi: 10.1186/s40792-024-01932-8.
Pulmonary abscess is a severe infection commonly seen in patients with chronic obstructive pulmonary disease, interstitial pneumonia, immune deficiency disease, drug-induced immunocompromised state, and congenital pulmonary disease. The treatment strategy in pregnant women with a pulmonary abscess is considered challenging since adverse effects on the fetus must be avoided to ensure safe delivery.
A 34-year-old female patient at 24 weeks of gestation (G2P1) was admitted to the Department of Obstetrics and Gynecology due to sudden right chest pain. The patient had no significant medical history, including congenital anomalies, and no history of drug addiction or smoking. Laboratory data indicated high levels of inflammation (white blood cell 12,000/µL, C-reactive protein 16.0 mg/dL), and computed tomography demonstrated a large intrapulmonary cyst located in the middle of the right lower lobe, with some fluid collection. As the patient had no medical history of congenital pulmonary anomalies, she was initially diagnosed with a pulmonary cyst infection and treated with intravenous antibiotics. However, the infection did not resolve for over a week, and a spike in fever developed after admission. There was no definitive evidence concerning the risk of preterm delivery and fetal abortion during non-obstetric surgery. However, to control the severely infected pulmonary abscess that was refractory to antibiotics and obtain a pathological diagnosis while saving the life of both the mother and fetus, we elected to perform an emergent right lower lobectomy by open thoracotomy with a fissureless maneuver after receiving informed consent. Postoperatively, the infection gradually improved, and the patient was discharged on the 16th postoperative day without any major complications in the mother or fetus. Although she later experienced coronavirus disease-19 at 29 weeks of gestation, a boy was born at 40th weeks of gestation without any complications. Pathologically, no infectious agents, malignancies, or congenital anomalies other than lung abscesses associated with the pulmonary infarction were observed. The mother and child were healthy 1 year postoperatively.
We experienced a rare case of a pulmonary abscess in a pregnant woman who needed an emergent right lower lobectomy to control the severe infection and obtain a correct pathological diagnosis. Under cooperation from an obstetrician and anesthesiologist, emergency pulmonary resection can be performed safely for serious abscess formation even for pregnant women who have several months left until delivery.
肺脓肿是一种严重感染,常见于慢性阻塞性肺疾病、间质性肺炎、免疫缺陷病、药物性免疫低下状态及先天性肺部疾病患者。对于患有肺脓肿的孕妇,治疗策略颇具挑战性,因为必须避免对胎儿产生不良影响以确保安全分娩。
一名孕24周(孕2产1)的34岁女性患者因突发右胸痛入住妇产科。该患者无重大病史,包括先天性异常,也无药物成瘾或吸烟史。实验室检查数据显示炎症指标升高(白细胞12,000/µL,C反应蛋白16.0mg/dL),计算机断层扫描显示右肺下叶中部有一个大的肺内囊肿,伴有一些液体积聚。由于该患者无先天性肺部异常病史,最初被诊断为肺囊肿感染并接受静脉抗生素治疗。然而,感染持续一周多未缓解,入院后出现发热高峰。关于非产科手术期间早产和胎儿流产风险尚无确切证据。然而,为了控制对抗生素难治的严重感染性肺脓肿并在挽救母婴生命的同时获得病理诊断,在获得知情同意后,我们选择通过无裂操作的开胸手术进行急诊右下肺叶切除术。术后,感染逐渐改善,患者术后第16天出院,母婴均无任何重大并发症。尽管她后来在孕29周时感染了新型冠状病毒,但在孕40周时顺产一名男婴,无任何并发症。病理检查显示,除了与肺梗死相关的肺脓肿外,未发现感染病原体、恶性肿瘤或先天性异常。术后1年母婴均健康。
我们遇到了一例罕见的孕妇肺脓肿病例,该患者需要急诊右下肺叶切除术以控制严重感染并获得正确的病理诊断。在产科医生和麻醉医生的协作下,即使对于距离分娩还有几个月的孕妇,紧急肺切除术也可安全进行以治疗严重的脓肿形成。