埃塞俄比亚新冠肺炎病例和死亡的地区及时间差异：从新冠肺炎强化监测与应对中汲取的经验教训。
Regional and temporal variations in COVID-19 cases and deaths in Ethiopia: Lessons learned from the COVID-19 enhanced surveillance and response.
作者信息
Teka Gizaw, Woldeab Adane, Dereje Nebiyu, Eshetu Frehywot, Gizachew Lehageru, Tazu Zelalem, Lisanwork Leuel, Tigabu Eyasu, Gebeyehu Ayele, Tayachew Adamu, Biru Mengistu, Berkessa Tsegaye, Keraleme Abrham, Bikale Fentahun, Shure Wolde, Agune Admikew, Haile Bizuwork, Addis Beza, Moges Muluken, Gonta Melaku, Hailemariam Aster, Binkley Laura, Nawaz Saira, Wang Shu-Hua, Mekuria Zelalem, Aklilu Ayalew, Aliy Jemal, Lulseged Sileshi, Girmay Abiy, Patrick Abok, Amare Berhanu, Delelegn Hulemenaw, Daves Sharon, Yimer Getnet, Abate Ebba, Wossen Mesfin, Melaku Zenebe, Gebreyes Wondwossen, Williams Desmond E, Abayneh Aschalew
机构信息
Ethiopian Public Health Institute, Addis Ababa, Ethiopia.
The Ohio State University Global One Health initiative (GOHi), Addis Ababa, Ethiopia.
出版信息
PLOS Glob Public Health. 2024 May 23;4(5):e0003175. doi: 10.1371/journal.pgph.0003175. eCollection 2024.
BACKGROUND
The COVID-19 pandemic is one of the most devastating public health emergencies of international concern to have occurred in the past century. To ensure a safe, scalable, and sustainable response, it is imperative to understand the burden of disease, epidemiological trends, and responses to activities that have already been implemented. We aimed to analyze how COVID-19 tests, cases, and deaths varied by time and region in the general population and healthcare workers (HCWs) in Ethiopia.
METHODS
COVID-19 data were captured between October 01, 2021, and September 30, 2022, in 64 systematically selected health facilities throughout Ethiopia. The number of health facilities included in the study was proportionally allocated to the regional states of Ethiopia. Data were captured by standardized tools and formats. Analysis of COVID-19 testing performed, cases detected, and deaths registered by region and time was carried out.
RESULTS
We analyzed 215,024 individuals' data that were captured through COVID-19 surveillance in Ethiopia. Of the 215,024 total tests, 18,964 COVID-19 cases (8.8%, 95% CI: 8.7%- 9.0%) were identified and 534 (2.8%, 95% CI: 2.6%- 3.1%) were deceased. The positivity rate ranged from 1% in the Afar region to 15% in the Sidama region. Eight (1.2%, 95% CI: 0.4%- 2.0%) HCWs died out of 664 infected HCWs, of which 81.5% were from Addis Ababa. Three waves of outbreaks were detected during the analysis period, with the highest positivity rate of 35% during the Omicron period and the highest rate of ICU beds and mechanical ventilators (38%) occupied by COVID-19 patients during the Delta period.
CONCLUSIONS
The temporal and regional variations in COVID-19 cases and deaths in Ethiopia underscore the need for concerted efforts to address the disparities in the COVID-19 surveillance and response system. These lessons should be critically considered during the integration of the COVID-19 surveillance system into the routine surveillance system.
背景
2019冠状病毒病（COVID-19）大流行是过去一个世纪发生的最具破坏性的国际关注的突发公共卫生事件之一。为确保做出安全、可扩展和可持续的应对，必须了解疾病负担、流行病学趋势以及对已实施活动的应对情况。我们旨在分析埃塞俄比亚普通人群和医护人员中COVID-19检测、病例和死亡情况如何随时间和地区变化。
方法
2021年10月1日至2022年9月30日期间，在埃塞俄比亚系统选取的64家医疗机构收集了COVID-19数据。纳入研究的医疗机构数量按比例分配到埃塞俄比亚的各个地区州。数据通过标准化工具和格式收集。对按地区和时间进行的COVID-19检测、检测出的病例以及登记的死亡情况进行了分析。
结果
我们分析了通过埃塞俄比亚COVID-19监测收集的215,024个人的数据。在总共215,024次检测中，确定了18,964例COVID-19病例（8.8%，95%置信区间：8.7%-9.0%），534例（2.8%，95%置信区间：2.6%-3.1%）死亡。阳性率从阿法尔地区的1%到锡达马地区的15%不等。在664名感染的医护人员中，有8名（1.2%，95%置信区间：0.4%-2.0%）死亡，其中81.5%来自亚的斯亚贝巴。在分析期间检测到三波疫情，奥密克戎时期阳性率最高达35%，德尔塔时期COVID-19患者占用重症监护病房床位和机械通气设备的比例最高（38%）。
结论
埃塞俄比亚COVID-19病例和死亡的时间和地区差异凸显了需要共同努力解决COVID-19监测和应对系统中的差异。在将COVID-19监测系统纳入常规监测系统的过程中，应认真考虑这些经验教训。
Zotero 插件