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利比里亚约翰·肯尼迪母婴中心(JFKMC)妊娠高血压疾病:负担、亚型和母婴结局。

Hypertensive Disorders in Pregnancy at the John F. Kennedy Maternity Center (JFKMC), Liberia: Burden, Sub-Types, and Maternofetal Outcome.

机构信息

Department of Obstetrics and Gynecology, John F. Kennedy Maternity Center, Monrovia. Liberia.

Department of Obstetrics and Gynecology, Faculty of Clinical Medicine, College of Health Sciences, Delta State University, Abraka, Delta State. Nigeria.

出版信息

Ethiop J Health Sci. 2023 Jul;33(4):601-610. doi: 10.4314/ejhs.v33i4.6.

Abstract

BACKGROUND

Hypertensive disorders in pregnancy (HDP) are a leading cause of maternal and fetal death, especially in a resource-constrained setting. There is no study from Liberia on the disorder. This pilot study aimed to determine the burden, sub-types, and maternal-fetal outcomes of hypertensive disorders in pregnancy at the John F. Kennedy Maternity Center (JFKMC), Liberia.

METHODS

From January 1 to December 31, 2020, the medical records of 130 pregnant and post-partum patients admitted with Hypertensive disorders in pregnancy (HDP) in a census method of sampling were retrieved, while 83.1% (108) were suitable for analysis in an institutional cross-sectional retrospective study in the department of obstetrics and gynecology at the John F. Kennedy Maternity Center, Liberia. The extracted information was analyzed using SPSS version 26. Results were presented in frequencies and percentages. The statistical association between categorical variables was subjected to the Chi-square test. The level of significance was set at a P-value of < 0.05.

RESULTS

There was an institutional prevalence of 3.0% of HDP. The maternal fatality rate was 12.3%, while the perinatal fatality rate was 14.3%. There was a significant association between HELLP syndrome and Severe pre-eclampsia with maternal death, P< 0.001. Prematurity, first minutes Apgar score <5, NICU admission, and low birth weight were associated with perinatal deaths (P <0.001).

CONCLUSION

HDP was an important contributor to maternal and perinatal deaths at the JFKMC, Liberia. Continuous support by the government and development partners for the provision of critical life-saving medical equipment at the JFKMC is recommended.

摘要

背景

妊娠高血压疾病(HDP)是孕产妇和胎儿死亡的主要原因,尤其是在资源有限的环境下。利比里亚尚无关于该疾病的研究。本初步研究旨在确定利比里亚约翰·肯尼迪母婴中心(JFKMC)妊娠高血压疾病的负担、亚型和母婴结局。

方法

2020 年 1 月 1 日至 12 月 31 日,采用普查方法对 130 名患有妊娠高血压疾病(HDP)的孕妇和产后患者的病历进行了检索,其中 83.1%(108 例)在利比里亚约翰·肯尼迪母婴中心妇产科进行了机构横断面回顾性研究。在 SPSS 版本 26 中分析提取的信息。结果以频率和百分比表示。对分类变量之间的统计学关联进行了卡方检验。显著性水平设为 P 值<0.05。

结果

HDP 的机构患病率为 3.0%。孕产妇死亡率为 12.3%,围产儿死亡率为 14.3%。HELLP 综合征与严重子痫前期与孕产妇死亡之间存在显著关联,P<0.001。早产、第 1 分钟 Apgar 评分<5、NICU 入院和低出生体重与围产儿死亡相关(P<0.001)。

结论

HDP 是 JFKMC 孕产妇和围产儿死亡的重要原因。建议政府和发展伙伴继续为 JFKMC 提供关键的救生医疗设备提供支持。

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