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肌肉挤压:一例因滥用健身前补充剂引发横纹肌溶解、肾衰竭和骨筋膜室综合征的病例研究

Crushing Muscles: A Case Study on Rhabdomyolysis, Renal Failure, and Compartment Syndrome Triggered by Pre-Workout Supplement Abuse.

作者信息

Altaf Faryal, Bhatt Vedangkumar, Venkatram Sindhaghatta, Diaz-Fuentes Gilda

机构信息

Internal Medicine, BronxCare Health System, Bronx, USA.

Medicine and Surgery, BronxCare Health System, Bronx, USA.

出版信息

Cureus. 2024 Apr 22;16(4):e58775. doi: 10.7759/cureus.58775. eCollection 2024 Apr.

Abstract

The use of steroids and protein-based dietary supplements for muscle enhancement is prevalent in contemporary society. While these products promise increased muscle mass and strength, they carry significant risks, including severe medical complications. The consumption of these supplements has been linked to adverse symptoms, including dehydration, gastrointestinal distress, dizziness, and alterations in heart rate and blood pressure, primarily due to ingredients like creatine, arginine, and caffeine. Following the proper dosage, ensuring adequate hydration, and consulting a healthcare provider to verify if the supplement's components could affect any pre-existing conditions is recommended. Indiscriminate use of these products, including taurine, can lead to serious side effects. We present a 36-year-old patient with severe rhabdomyolysis, life-threatening acid-base imbalance, renal and liver injury, and peripheral neuropathy associated with the use of performance-enhanced unregulated supplements and exercise. This case highlights the importance of recognizing and managing complications related to exercise-aid supplements, emphasizing early identification and management. Increasing social awareness and research on those products is highly needed to avoid supplement-associated complications and potential long-term disabilities.

摘要

在当代社会,使用类固醇和蛋白质类膳食补充剂来增强肌肉的现象很普遍。虽然这些产品承诺能增加肌肉量和力量,但它们存在重大风险,包括严重的医学并发症。食用这些补充剂与不良症状有关,包括脱水、胃肠道不适、头晕以及心率和血压变化,主要是由于肌酸、精氨酸和咖啡因等成分。建议遵循正确的剂量、确保充足的水分摄入,并咨询医疗保健人员以核实补充剂的成分是否会影响任何已有的病症。不加区分地使用这些产品,包括牛磺酸,可能会导致严重的副作用。我们介绍了一名36岁的患者,其患有严重的横纹肌溶解症、危及生命的酸碱失衡、肾和肝损伤以及与使用未经监管的增强性能补充剂和运动相关的周围神经病变。该病例凸显了认识和处理与运动辅助补充剂相关并发症的重要性,强调早期识别和处理。迫切需要提高社会对这些产品的认识并开展相关研究,以避免与补充剂相关的并发症和潜在的长期残疾。

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