Ejikeme Chidinma, Alyacoub Ramez, Elkattawy Sherif, Shankar Tanya, Yuridullah Ruhin
Internal Medicine, Rutgers New Jersey Medical School/Trinitas Regional Medical Center, Elizabeth, USA.
Internal Medicine, St. Joseph's Univeristy Medical Center, Paterson, USA.
Cureus. 2021 Mar 31;13(3):e14202. doi: 10.7759/cureus.14202.
Rhabdomyolysis is a complex medical condition characterized by muscle necrosis and the release of intracellular components into the circulation. Although its most common cause is a direct traumatic injury, it can result from non-traumatic factors as well, including infection, toxins, and drugs. Serum creatine phosphokinase (CPK) levels are usually elevated in this condition and they correlate with the severity of the muscle damage (the higher the CPK peak, the greater the magnitude of muscle damage), although lower levels of CPK do not necessarily rule it out. The common complications associated with rhabdomyolysis include acute kidney injury, compartment syndrome, and, in rare cases, peripheral neuropathy. In this report, we present a case of a young patient, with a history of alcohol abuse, who presented with bilateral numbness of the feet post-immobilization and was subsequently found to have severe rhabdomyolysis.
横纹肌溶解症是一种复杂的医学病症,其特征为肌肉坏死以及细胞内成分释放进入血液循环。尽管其最常见的病因是直接创伤性损伤,但也可能由非创伤性因素引起,包括感染、毒素和药物。在这种情况下,血清肌酸磷酸激酶(CPK)水平通常会升高,并且它们与肌肉损伤的严重程度相关(CPK峰值越高,肌肉损伤的程度越大),尽管较低的CPK水平并不一定排除该病症。与横纹肌溶解症相关的常见并发症包括急性肾损伤、骨筋膜室综合征,以及在罕见情况下的周围神经病变。在本报告中,我们介绍了一例有酗酒史的年轻患者,该患者在固定后出现双足麻木,随后被发现患有严重的横纹肌溶解症。