Chen Jie, Xiao Yan, Yan Chaofang, Li Xiaoju, Zhang Yafang, Chen Ying, Huang Yuan, Deng Rui
School of Public Health, Kunming Medical University, Kunming, Yunnan, People's Republic of China.
Foreign Languages Department, Kunming Medical University, Kunming, Yunnan, People's Republic of China.
J Multidiscip Healthc. 2024 May 19;17:2425-2439. doi: 10.2147/JMDH.S463640. eCollection 2024.
With population aging, individuals in underdeveloped areas may experience a higher prevalence of chronic non-communicable diseases (NCDs), a lower level of health-related quality of life (HRQoL), and distinct lifestyles. However, this triadic association remains inadequately studied, particularly regarding the role of health lifestyle. This study aims to examine the relationship between the number of NCDs and HRQoL, while considering the moderating effect of health lifestyle among middle-aged and older adults residing in resource-limited areas.
This cross-sectional study was conducted in Yunnan Province from July to December 2022. Participants completed a self-report questionnaire related to socio-demographic information, NCDs conditions, health lifestyle status, and HRQoL, which was assessed using the EuroQol five-dimension five-level (EQ-5D-5L) scale. Hierarchical regression and simple slope tests were used to examine the moderating effect of health lifestyle.
Out of the total 2704 participants, 57.91% presented at least one NCD. The mean scores for health lifestyle and health utility value were 11.109 and 0.944 respectively. The number of NCDs was negatively associated with health utility value, while positively correlated with the health lifestyle score (<0.001). The results of hierarchical regression indicated that health lifestyle exerted a negative moderating effect on the relationship between the number of NCDs and HRQoL (=0.006, <0.001), which was also observed for specific health-related behaviors such as sleep duration (=0.013, <0.001), physical examination attendance (=0.006, <0.05) and physical activity (=0.013, <0.001).
These findings highlight the crucial role of a healthy lifestyle in attenuating the association between the number of NCDs and HRQoL. Recognizing the potential modulating influence of a healthy lifestyle in this relationship could be pivotal for developing effective interventions for this population, even within resource-constrained rural settings.
随着人口老龄化，欠发达地区的个体可能患慢性非传染性疾病（NCDs）的患病率更高、健康相关生活质量（HRQoL）水平更低，且生活方式各异。然而，这种三元关联仍未得到充分研究，尤其是关于健康生活方式的作用。本研究旨在探讨非传染性疾病数量与健康相关生活质量之间的关系，同时考虑居住在资源有限地区的中老年人健康生活方式的调节作用。
本横断面研究于2022年7月至12月在云南省进行。参与者完成了一份自我报告问卷，内容涉及社会人口学信息、非传染性疾病状况、健康生活方式状况和健康相关生活质量，后者使用欧洲五维五级量表（EQ-5D-5L）进行评估。采用分层回归和简单斜率检验来检验健康生活方式的调节作用。
在总共2704名参与者中，57.91%的人至少患有一种非传染性疾病。健康生活方式和健康效用值的平均得分分别为11.109和0.944。非传染性疾病的数量与健康效用值呈负相关，而与健康生活方式得分呈正相关（<0.001）。分层回归结果表明，健康生活方式对非传染性疾病数量与健康相关生活质量之间的关系具有负向调节作用（=0.006，<0.001），对于特定的健康相关行为，如睡眠时间（=0.013，<0.001）、体检参与情况（=0.006，<0.05）和体育活动（=0.013，<0.001）也观察到了这种情况。
这些发现凸显了健康生活方式在减弱非传染性疾病数量与健康相关生活质量之间关联方面的关键作用。认识到健康生活方式在这种关系中的潜在调节影响，对于为这一人群制定有效的干预措施可能至关重要，即使是在资源有限的农村地区。
