Di Fusco Stefania Angela, Mocini Edoardo, Gori Mauro, Iacoviello Massimo, Bilato Claudio, Corda Marco, De Luca Leonardo, Di Marco Massimo, Geraci Giovanna, Iacovoni Attilio, Milli Massimo, Navazio Alessandro, Pascale Vittorio, Riccio Carmine, Scicchitano Pietro, Tizzani Emanuele, Gabrielli Domenico, Grimaldi Massimo, Colivicchi Furio, Oliva Fabrizio
U.O.C. Cardiologia Clinica e Riabilitativa, Dipartimento di Emergenza e Accettazione, Presidio Ospedaliero San Filippo Neri-ASL Roma 1, via Martinotti 20, 00135 Roma, Italy.
Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Eur Heart J Suppl. 2024 May 16;26(Suppl 2):ii221-ii235. doi: 10.1093/eurheartjsupp/suae031. eCollection 2024 Apr.
Obesity is a chronic and relapsing disease characterized by the interaction between individual predispositions and an obesogenic environment. Recent advances in understanding the mechanisms of energetic homoeostasis paved the way to more effective therapeutic approaches compared with traditional treatments. Since obesity is a complex disease, it necessitates a multi-disciplinary approach whose implementation remains challenging. Nonetheless, emerging pharmacological interventions appear promising. Currently, therapeutic success is discreet in the short term but often fails to maintain long-term weight loss due to a high likelihood of weight regain. Cardiologists play a key role in managing patients with obesity, yet often lack familiarity with its comprehensive management. The aim of this document is to summarize knowledge to consolidate essential knowledge for clinicians to effectively treat patients living with obesity. The paper emphasizes the pivotal role of a strong patient-clinician relationship in navigating successful treatment. We analyse the criteria commonly used to diagnose obesity and point out the strengths and limitations of different criteria. Furthermore, we discuss the role of obesiologists and the contributions of cardiologists. In addition, we detail key components of effective therapeutic strategies, including educational aspects and pharmacological options.
肥胖是一种慢性复发性疾病,其特征是个体易感性与致肥胖环境之间的相互作用。与传统治疗方法相比,在理解能量稳态机制方面的最新进展为更有效的治疗方法铺平了道路。由于肥胖是一种复杂的疾病,因此需要采取多学科方法,但其实施仍然具有挑战性。尽管如此,新兴的药物干预措施似乎很有前景。目前,治疗在短期内取得了一定成效,但由于体重反弹的可能性很高,往往无法维持长期体重减轻。心脏病专家在肥胖患者的管理中起着关键作用,但往往对肥胖的综合管理缺乏了解。本文的目的是总结相关知识,为临床医生有效治疗肥胖患者巩固基本知识。本文强调了牢固的医患关系在成功治疗中的关键作用。我们分析了常用于诊断肥胖的标准,并指出了不同标准的优缺点。此外,我们讨论了肥胖症专家的作用以及心脏病专家的贡献。此外,我们详细介绍了有效治疗策略的关键组成部分,包括教育方面和药物选择。