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[使用心肌保护技术对心脏手术前后人体心肌进行的超微结构-形态计量学比较研究]

[Comparative ultrastructural-morphometric studies of the human myocardium before and following heart surgery using myocardial protection].

作者信息

Matchew S T, Welkowa S W

出版信息

Z Exp Chir Transplant Kunstliche Organe. 1985;18(5):298-307.

PMID:3878637
Abstract

Ultrastructural morphometric changes of the myocardium were reported after biopsy during the aortic occlusion time and during the reperfusion time throughout cardiosurgery in two groups of patients: Group AKB (aorto-coronary bypass): The mitochondria are increasing in the number and are decreasing in the size. The signs of biogenesis are shown. The condition after reperfusion is good. Group AVR (aortic valve replacement): The mitochondria are decreasing in the number and increasing in the size. These are signs of swelling and/or fusion. The condition after reperfusion is not so good. Therefore patients with AVR are a higher risk for cardiosurgery than the patients with chronic ischemic heart disease (AKB).

摘要

在两组患者心脏手术的主动脉阻断期和再灌注期进行心肌活检后,报告了心肌的超微结构形态计量学变化:AKB组(主动脉冠状动脉搭桥术):线粒体数量增加,大小减小。显示出生物发生的迹象。再灌注后的情况良好。AVR组(主动脉瓣置换术):线粒体数量减少,大小增加。这些是肿胀和/或融合的迹象。再灌注后的情况不太好。因此,与慢性缺血性心脏病患者(AKB组)相比,AVR组患者心脏手术的风险更高。

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