Haraphongse M, Fraser R S, Rossall R E, Fisk R L, Basuldo C A, Gelfand E T, Callaghan J C
Can J Surg. 1978 Mar;21(2):101-3.
The operative results in 32 patients who underwent aortic valve replacement with aortic occlusion and normothermic myocardium (group 1) were compared with 54 similar patients in whom the myocardium was protected by hypothermic coronary perfusion through the aortic root (group 2). The operative mortality and the incidence of heart failure, subendocardial ischemia and myocardial infarction were the same in the two groups. The maximal concentrations of cardiac enzymes after operation in group 2 patients were significantly lower than those in group 1. The postoperative cardiac performance was significantly different in that only 5.6% of group 2 patients required inotropic agents after operation compared with 25% of group 1 patients. The patients in group 2 were easier to defibrillate after cardiopulmonary bypass.
将32例接受主动脉阻断和常温心肌保护下行主动脉瓣置换术的患者（第1组）的手术结果，与54例通过主动脉根部低温冠状动脉灌注保护心肌的类似患者（第2组）进行比较。两组的手术死亡率、心力衰竭、心内膜下缺血和心肌梗死的发生率相同。第2组患者术后心肌酶的最大浓度显著低于第1组。术后心脏功能有显著差异，即第2组仅5.6%的患者术后需要使用正性肌力药物，而第1组为25%。第2组患者在体外循环后更容易除颤。
