Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, MN, USA.
Division of General Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Curr Gastroenterol Rep. 2024 Aug;26(8):200-210. doi: 10.1007/s11894-024-00934-8. Epub 2024 May 24.
Enteral nutrition (EN) therapy can provide vital nutrition support for patients with various medical conditions as long as it is indicated and supported by ethical reasoning. This review seeks to offer a detailed account of the history of EN development, highlighting key milestones and recent advances in the field. Additionally, it covers common complications associated with EN and their management.
After years of research and development, we have reached newer generations of enteral feeding formulations, more options for enteral tubes and connectors, and a better understanding of EN therapy challenges. Given the availability of many different formulas, selecting a feeding formula with the best evidence for specific indications for enteral feeding is recommended. Initiation of enteral feeding with standard polymeric formula remains the standard of care. Transition to small-bore connectors remains suboptimal. Evidence-based practices should be followed to recognize and reduce possible enteral feeding complications early.
只要符合伦理推理并得到支持,肠内营养(EN)治疗就能为各种医疗状况的患者提供重要的营养支持。本综述旨在详细介绍 EN 发展的历史,重点介绍该领域的关键里程碑和最新进展。此外,还涵盖了常见的肠内营养相关并发症及其处理方法。
经过多年的研究和开发,我们已经研发出新一代的肠内喂养配方、更多种类的肠内管和连接器,并且对肠内营养治疗的挑战有了更深入的了解。鉴于有多种不同的配方,建议根据肠内喂养的具体适应证选择具有最佳证据的喂养配方。使用标准聚合配方开始肠内喂养仍然是标准的治疗方法。向小口径连接器的过渡仍然不理想。应遵循循证实践,及早识别和减少可能的肠内喂养并发症。