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休克指数在老年患者中的预测作用强于年轻患者。

Shock Index is a Stronger Predictor of Outcomes in Older Compared to Younger Patients.

机构信息

Westchester Medical Center, New York Medical College, Valhalla, New York.

Westchester Medical Center, New York Medical College, Valhalla, New York.

出版信息

J Surg Res. 2024 Aug;300:8-14. doi: 10.1016/j.jss.2024.04.064. Epub 2024 May 23.

Abstract

INTRODUCTION

The shock index (SI) is a known predictor of unfavorable outcomes in trauma. This study seeks to examine and compare the SI values between geriatric patients and younger adults.

METHODS

We conducted a retrospective study of the Trauma Quality Improvement Program database from 2017 to 2019. All patients≥ 25 y with injury severity score ≥ 16 were included. Age groups were defined as 25-44 y (group A), 45-64 y (group B), and ≥65 y (group C). SI was calculated for all patients. The primary outcome was mortality and secondary outcomes were need for blood transfusion and need for major surgical intervention (consisting angiography, exploratory laparotomy, and thoracotomy).

RESULTS

A total of 244,943 patients were studied. The SI was highest in group A (0.82 ± 0.33) and lowest in group C (0.62 ± 0.30) (P < 0.001). Mortality rate of group C (17%) was significantly higher than group A (9.7%) and B (11.3%) (P < 0.001). In group A, each 0.1 increase in SI was associated with mortality (odds ratio [OR] = 1.079), need for blood transfusion (OR = 1.225) and need for major surgical intervention (OR = 1.347) (P < 0.001 for all). In group C, each 0.1 increase in SI was associated with mortality (OR = 1.126), need for blood transfusion (OR = 1.318), and need for major surgical intervention (OR = 1.648) (P < 0.001 for all). The area under the curve of SI was significantly higher in group C compared to other groups for needing a major surgical intervention and need for blood transfusion (P < 0.05 for both).

CONCLUSIONS

These results highlight the significance of the SI as a valuable indicator in geriatric patients with severe trauma. The findings show that SI predicts outcomes in geriatrics more strongly than in younger counterparts.

摘要

简介

休克指数(SI)是创伤不良结局的已知预测因子。本研究旨在检查和比较老年患者和年轻成人的 SI 值。

方法

我们对 2017 年至 2019 年创伤质量改进计划数据库进行了回顾性研究。所有损伤严重程度评分≥16 的≥25 岁患者均纳入研究。年龄组定义为 25-44 岁(A 组)、45-64 岁(B 组)和≥65 岁(C 组)。为所有患者计算 SI。主要结局为死亡率,次要结局为输血需求和主要手术干预(包括血管造影、剖腹探查术和开胸术)的需求。

结果

共研究了 244943 名患者。A 组的 SI 最高(0.82±0.33),C 组最低(0.62±0.30)(P<0.001)。C 组(17%)的死亡率明显高于 A 组(9.7%)和 B 组(11.3%)(P<0.001)。在 A 组中,SI 每增加 0.1,死亡率(比值比[OR]1.079)、输血需求(OR 1.225)和主要手术干预(OR 1.347)的风险就会增加(所有 P<0.001)。在 C 组中,SI 每增加 0.1,死亡率(OR 1.126)、输血需求(OR 1.318)和主要手术干预(OR 1.648)的风险就会增加(所有 P<0.001)。与其他组相比,C 组 SI 对需要主要手术干预和输血的曲线下面积显著更高(均 P<0.05)。

结论

这些结果强调了 SI 作为严重创伤老年患者有价值指标的重要性。研究结果表明,SI 对老年患者的预后预测作用强于年轻患者。

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