Choi Yee Nam Candice, Martel-Sauvageau Vincent, Breton Myriam, Lavoie Monica, Laforce Robert, Bouvier Liziane
School of Communication Sciences and Disorders, McGill University, Montréal, QC H3A 0G4, Canada.
Faculté de Médecine, Université Laval, Québec, QC G1V 0A6, Canada.
Brain Sci. 2024 Apr 24;14(5):417. doi: 10.3390/brainsci14050417.
Primary progressive apraxia of speech (PPAOS) is a neurodegenerative syndrome characterized by the progressive and initially isolated or predominant onset of difficulties in the planning/programming of movements necessary for speech production and can be accompanied by dysarthria. To date, no study has used an evidence-based treatment to address phonation control in patients with PPAOS. The aim of this study was to evaluate the feasibility and efficacy of LSVT LOUD as a treatment for phonatory control in speakers with PPAOS. Three speakers with PPAOS received LSVT LOUD therapy, and changes in phonatory control, voice quality and prosody were measured immediately, and one, four and eight weeks after the end of the treatment. Overall, the results suggest that the treatment is feasible and could improve voice quality, intensity, and control in some patients with PPAOS. The generalization of the results is also discussed.
原发性进行性言语失用症（PPAOS）是一种神经退行性综合征，其特征是在言语产生所需运动的计划/编程方面逐渐出现且最初孤立或占主导地位的困难，并可能伴有构音障碍。迄今为止，尚无研究采用循证治疗来解决PPAOS患者的发声控制问题。本研究的目的是评估大声言语治疗（LSVT LOUD）作为PPAOS患者发声控制治疗方法的可行性和疗效。三名PPAOS患者接受了LSVT LOUD治疗，并在治疗结束后立即、1周、4周和8周测量了发声控制、嗓音质量和韵律的变化。总体而言，结果表明该治疗是可行的，并且可以改善一些PPAOS患者的嗓音质量、强度和控制能力。同时也讨论了结果的普遍性。
