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乳糜泻的全球随访方法

Global Approach to Follow-Up of Celiac Disease.

作者信息

Perez-Junkera Gesala, Ruiz de Azua Lorea, Vázquez-Polo Maialen, Lasa Arrate, Fernandez Gil María Pilar, Txurruka Itziar, Navarro Virginia, Larretxi Idoia

机构信息

GLUTEN3S Research Group, Department of Nutrition and Food Science, University of the Basque Country, 01006 Vitoria-Gasteiz, Spain.

Children's National Hospital 111 Michigan Avenue NW, Washington, DC 20010, USA.

出版信息

Foods. 2024 May 8;13(10):1449. doi: 10.3390/foods13101449.

Abstract

Celiac disease, an autoimmune disorder induced by the ingestion of gluten, affects approximately 1.4% of the population. Gluten damages the villi of the small intestine, producing symptoms such as abdominal pain, bloating and a subsequent loss of nutrient absorption, causing destabilization of the nutritional status. Moreover, gluten can trigger extra intestinal symptoms, such as asthma or dermatitis, but also mental disorders such as depression or anxiety. Moreover, people suffering from celiac disease sometimes feel misunderstood by society, mainly due to the lack of knowledge about the disease and the gluten-free diet. Thus, the treatment and follow-up of patients with celiac disease should be approached from different perspectives, such as the following: (1) a clinical perspective: symptomatology and dietary adherence monitorization; (2) nutritional assessment: dietary balance achievement; (3) psychological assistance: mental disorders avoidance; and (4) social inclusion: educating society about celiac disease in order to avoid isolation of those with celiac disease. The aim of this narrative review is to gain deep insight into the different strategies that currently exist in order to work on each of these perspectives and to clarify how the complete approach of celiac disease follow-up should be undertaken so that the optimum quality of life of this collective is reached.

摘要

乳糜泻是一种因摄入麸质而引发的自身免疫性疾病,影响着约1.4%的人口。麸质会损害小肠绒毛,引发腹痛、腹胀等症状,进而导致营养吸收不良,使营养状况不稳定。此外,麸质还会引发肠道外症状,如哮喘或皮炎,以及精神障碍,如抑郁或焦虑。此外,乳糜泻患者有时会觉得不被社会理解,主要是因为缺乏对该疾病和无麸质饮食的了解。因此,应从不同角度对乳糜泻患者进行治疗和随访,如下所示:(1)临床角度:监测症状和饮食依从性;(2)营养评估:实现饮食平衡;(3)心理援助:避免精神障碍;(4)社会融入:向社会宣传乳糜泻知识,以避免乳糜泻患者被孤立。本叙述性综述的目的是深入了解目前针对这些不同角度所采用的不同策略,并阐明应如何全面开展乳糜泻随访工作,从而使这一群体达到最佳生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abc0/11119929/afc6d49a3773/foods-13-01449-g001.jpg

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