Kopp Dannell J, Larson Robert L, Lancaster Phillip A, White Bradley J, Smith Kristen J, Pendell Dustin L
Beef Cattle Institute, Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA.
Private Consultant, Baldwin City, KS 66006, USA.
Animals (Basel). 2024 May 10;14(10):1423. doi: 10.3390/ani14101423.
Metaphylactic antibiotic use in feeder cattle is a common practice to control respiratory disease. Antimicrobial stewardship is important to ensure continued efficacy and to protect animal welfare. The objective of this study is to identify characteristics of cohorts of cattle that had not received metaphylaxis that would have benefited economically from the use of metaphylaxis. Cohorts ( = 12,785; 2,206,338 head) from 13 feedlots that did not receive metaphylaxis were modeled using an economic model to estimate net returns for three metaphylactic options. Logistic regression models with covariates for entry weight, sex, average daily weight gain, number of animals per cohort, and days on feed, with feedlot as a random effect, were used to determine the model-adjusted probability of cohorts benefiting economically from metaphylaxis. Most (72%) cohorts in this data set that had not received metaphylaxis at arrival would not economically benefit from metaphylaxis. Sex, entry weight category, number of cattle in the cohort, and average daily weight gain were associated with the likelihood of benefitting economically from metaphylaxis. The results illustrated that cattle cohort demographics influenced the probability that cohorts would benefit economically from metaphylaxis and the type of metaphylaxis utilized, and integrating this information has the potential to influence the metaphylaxis decision.
在育肥牛中预防性使用抗生素是控制呼吸道疾病的常见做法。抗菌药物管理对于确保持续疗效和保护动物福利非常重要。本研究的目的是确定未接受预防性用药但使用预防性用药会在经济上受益的牛群特征。使用经济模型对来自13个未接受预防性用药的饲养场的牛群（n = 12,785；2,206,338头）进行建模，以估计三种预防性用药方案的净收益。使用带有入栏体重、性别、平均日增重、每群动物数量和饲养天数协变量的逻辑回归模型，并将饲养场作为随机效应，来确定牛群从预防性用药中获得经济收益的模型调整概率。该数据集中大多数（72%）到达时未接受预防性用药的牛群不会从预防性用药中获得经济收益。性别、入栏体重类别、牛群中的牛数量和平均日增重与从预防性用药中获得经济收益的可能性相关。结果表明，牛群的人口统计学特征影响了牛群从预防性用药中获得经济收益的概率以及所使用的预防性用药类型，整合这些信息有可能影响预防性用药决策。
