Ooi Theng Choon, Rivan Nurul Fatin Malek, Shahar Suzana, Rajab Nor Fadilah, Ismail Munirah, Singh Devinder Kaur Ajit
Premier Integrated Labs Sdn. Bhd., Kuala Lumpur 55100, Malaysia.
Centre for Healthy Ageing and Wellness, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur 50300, Malaysia.
J Clin Med. 2024 May 12;13(10):2854. doi: 10.3390/jcm13102854.
: Joint pain has been recognized as one of the major causes of limitations in mobility, functional decline, and consequently declined quality of life in older adults. Hence, this study aimed to identify the predictors, protective factors, and adverse outcomes of joint pain in community-dwelling older adults. : In this Long-term Research Grant Scheme-Towards Useful Ageing (LRGS-TUA) longitudinal study, a total of 1005 older participants aged 60 years and above who were successfully followed up after five years were included in the analysis. The participants self-reported their joint pain status at baseline and during the fifth year. Subsequently, the baseline characteristics were used to predict changes in joint pain status. Adverse outcomes related to joint pain were evaluated based on the participants' joint pain statuses. : Results showed that being female, having diabetes mellitus, and higher body mass index were associated with the incidence of joint pain. Meanwhile, increased intake of pantothenic acid and higher levels of blood albumin levels were associated with recovery from joint pain. Participants with persistent joint pain at baseline and follow-up showed higher levels of depression and disability compared to individuals who never experience any joint pain. However, participants who had recovered from joint pain did not differ significantly from those without joint pain at baseline and follow-up in these measures. : By identifying the modifiable risk factors, factors associated with recovery, and adverse outcomes related to joint pain, this study adds to current evidence that may contribute to further management strategies for joint pain in older adults.
关节疼痛已被公认为是导致老年人行动受限、功能衰退以及生活质量下降的主要原因之一。因此,本研究旨在确定社区居住老年人关节疼痛的预测因素、保护因素及不良后果。
在这项长期研究资助计划——迈向健康老龄化(LRGS-TUA)的纵向研究中,共有1005名60岁及以上的老年参与者被纳入分析,他们在五年后成功接受了随访。参与者在基线期和第五年自行报告其关节疼痛状况。随后,利用基线特征来预测关节疼痛状况的变化。基于参与者的关节疼痛状况评估与关节疼痛相关的不良后果。
结果显示,女性、患有糖尿病以及较高的体重指数与关节疼痛的发生率相关。同时,泛酸摄入量增加和血液白蛋白水平较高与关节疼痛的恢复相关。与从未经历过任何关节疼痛的个体相比,在基线期和随访期持续存在关节疼痛的参与者表现出更高水平的抑郁和残疾。然而,在这些指标上,从关节疼痛中恢复的参与者与在基线期和随访期无关节疼痛的参与者相比,并无显著差异。
通过确定可改变的风险因素、与恢复相关的因素以及与关节疼痛相关的不良后果,本研究为现有证据增添了内容,这可能有助于进一步制定老年人关节疼痛的管理策略。