Department of General, Minimally Invasive and Elderly Surgery, Collegium Medicum, University of Warmia and Mazury, Niepodległosci 44 St., 10-045 Olsztyn, Poland.
Department of Anesthesiology and Intensive Care, Children's Memorial Health Institute, Av. Dzieci Polskich 20, 04-730 Warsaw, Poland.
Medicina (Kaunas). 2024 Apr 24;60(5):688. doi: 10.3390/medicina60050688.
Gastroesophageal reflux disease (GERD) is a common disease affecting approximately 20% of the adult population. This study aimed to compare the results of laparoscopic Nissen fundoplication (LNF) in the treatment of GERD in patients of different age groups. A retrospective analysis was performed on patients who underwent LNF in one surgical department between 2014 and 2018. Patients were divided into three groups based on age: under 40 years of age, 40-65 years of age, and over 65 years of age. A total of 111 patients (44.1% women) were analyzed in this study. The mean age was 50.2 ±15 years, and the mean follow-up was 50 months ± 16.6 months. Recurrence of symptoms occurred in 23%, 20%, and 23% in each age group, respectively ( = 0.13), and 85%, 89%, and 80% of patients from the respective groups reported that they would recommend the surgery to their relatives ( = 0.66). Furthermore, 83%, 92%, and 73% of patients from the respective age groups reported that they would undergo the surgery again with the knowledge they now had ( = 0.16). Given these results and observations, LNF has been shown to be a good method of treatment for GERD in every age group. In our study, there were no differences found in terms of satisfaction with surgery and associated recommendations between the studied age groups.
胃食管反流病（GERD）是一种常见疾病，影响大约 20%的成年人口。本研究旨在比较腹腔镜 Nissen 胃底折叠术（LNF）治疗不同年龄组 GERD 的结果。对 2014 年至 2018 年间在一个外科部门接受 LNF 的患者进行回顾性分析。根据年龄将患者分为三组：<40 岁、40-65 岁和>65 岁。本研究共分析了 111 例患者（44.1%为女性）。平均年龄为 50.2±15 岁，平均随访时间为 50 个月±16.6 个月。在每个年龄组中，症状复发的发生率分别为 23%、20%和 23%（=0.13），分别有 85%、89%和 80%的患者表示会向亲属推荐该手术（=0.66）。此外，分别有 83%、92%和 73%的患者表示，如果他们现在知道手术的相关知识，他们会再次接受手术（=0.16）。鉴于这些结果和观察，LNF 已被证明是治疗 GERD 的一种有效方法，适用于各个年龄段。在我们的研究中，在对手术的满意度和相关推荐方面，不同研究年龄组之间没有差异。
