Department of Physiotherapy, University of the Western Cape (UWC), 10 Blanckenberg Road, Bellville, Cape Town 7530, South Africa.
Department of Rehabilitation Medicine, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
Sensors (Basel). 2024 May 15;24(10):3131. doi: 10.3390/s24103131.
Sensory peripheral neuropathy is a common complication of diabetes mellitus and the biggest risk factor for diabetic foot ulcers. There is currently no available treatment that can reverse sensory loss in the diabetic population. The application of mechanical noise has been shown to improve vibration perception threshold or plantar sensation (through stochastic resonance) in the short term, but the therapeutic use, and longer-term effects have not been explored. In this study, vibrating insoles were therapeutically used by 22 participants, for 30 min per day, on a daily basis, for a month by persons with diabetic sensory peripheral neuropathy. The therapeutic application of vibrating insoles in this cohort significantly improved VPT by an average of 8.5 V ( = 0.001) post-intervention and 8.2 V ( < 0.001) post-washout. This statistically and clinically relevant improvement can play a role in protection against diabetic foot ulcers and the delay of subsequent lower-extremity amputation.
感觉周围神经病是糖尿病的常见并发症，也是糖尿病足溃疡的最大危险因素。目前尚无治疗方法可以逆转糖尿病患者的感觉丧失。机械噪声的应用已被证明可以在短期内改善振动感觉阈值或足底感觉（通过随机共振），但治疗用途和长期效果尚未得到探索。在这项研究中，振动鞋垫通过 22 名患有糖尿病感觉周围神经病的参与者，每天治疗 30 分钟，持续一个月。在这个队列中，振动鞋垫的治疗应用在干预后平均显著提高了 8.5 V（=0.001）的 VPT，在洗脱后提高了 8.2 V（<0.001）。这种具有统计学意义和临床意义的改善可以在预防糖尿病足溃疡和延迟后续下肢截肢方面发挥作用。
