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一组哮喘患者中两个外周标志物之间的关联。

Connection between two peripherical markers in a group of asthmatic patients.

作者信息

Monteseirín F J, Conejero A, Conde J, Prados M, Toledo F, Muñoz J, García J, Luna I, Romero E

出版信息

Allergol Immunopathol (Madr). 1985 Nov-Dec;13(6):509-12.

PMID:3879576
Abstract

We have studied the goniometric value of the tda angle and the alpha 1 antitrypsin phenotypes in a group of thirty atopic patients with the following patterns: 1) they were affected with asthma, atopic dermatitis and rhinitis. 2) they presented positive prick skin tests for pneumo-allergens and had. 3) positive allergic antecedents. There exists a significant statistical value for the lower tda angle in the right hand, in the MZ phenotypes of alpha 1 antitrypsin bearers, with P less than 0.05 significance. In the left hand there are many individual values that are identical (62% of the total test effected) thus the statistical methods cannot be applied satisfactorily, bearing in mind the significant difference as the statistical group recognized. From this and other previous works, we can conclude that an individual whose right hand tda angle reaches values near 75%, and with a MZ phenotype of alpha 1 antitrypsin, has a greater possibility of pertaining to one of the groups of asthma, atopic dermatitis and rhinitis symptomatology.

摘要

我们研究了30名特应性患者的tda角的测角值和α1抗胰蛋白酶表型,这些患者具有以下特征:1)患有哮喘、特应性皮炎和鼻炎。2)对气源性变应原的皮肤点刺试验呈阳性。3)有阳性过敏史。在α1抗胰蛋白酶携带者的MZ表型中,右手较低的tda角存在显著的统计学值,P值小于0.05,具有显著性。在左手,有许多个体值是相同的(占总测试的62%),因此考虑到作为统计学组所认可的显著差异,统计方法不能令人满意地应用。从这项研究和其他先前的研究中,我们可以得出结论,右手tda角达到接近75%的值且具有α1抗胰蛋白酶MZ表型的个体,更有可能属于哮喘、特应性皮炎和鼻炎症状群中的一组。

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