Ullern M, Massin M, Pozzo J M, Boureau C
J Fr Ophtalmol. 1985;8(11):721-8.
Irido-corneal endothelial syndrome regroups three disorders including: endotheliopathy, peripheral anterior synechiae and iris changes. According to the aspect of these abnormalities, three syndromes are described: essential iris atrophy, Chandler's syndrome and iris naevus (Cogan-Reese) syndrome. Endothelial changes studied by specular microscopy are typical: in early stages, a rounding off cell angles and intracellular blackout areas can be seen; in former stages, black out areas increase and there is a disruption of the regular mosaic. These features are a major point for differential diagnosis. We present six cases reports among which three where effectively diagnosed as iridocorneal endothelial syndrome and three were not.
内皮病变、周边前粘连和虹膜改变。根据这些异常表现,描述了三种综合征:原发性虹膜萎缩、钱德勒综合征和虹膜痣(科根-里斯)综合征。通过镜面显微镜检查研究的内皮变化具有典型特征:在早期阶段,可以看到细胞角变圆和细胞内遮光区域;在后期阶段,遮光区域增加,规则的镶嵌结构遭到破坏。这些特征是鉴别诊断的要点。我们呈现六例病例报告,其中三例被有效诊断为虹膜角膜内皮综合征,三例未被诊断为此病。