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长期轮班工作、夜班工作、睡眠不足与中风的关系:系统评价和荟萃分析。

Relationship between long-term shift work; night work; sleep deficiency and stroke: A systematic review and meta-analysis.

机构信息

Chinese Medicine Resource Center, China Academy of Chinese Medical Sciences, Beijing, 100700, China.

Shaanxi University of Chinese Medicine, Xianyang, 712046, China; Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, 712000, China.

出版信息

Sleep Med. 2024 Jul;119:499-504. doi: 10.1016/j.sleep.2024.05.031. Epub 2024 May 17.

Abstract

BACKGROUND

The association between shift/night work and the risk of stroke is not supported by strong evidence.

OBJECTIVE

This study aimed to obtain evidence of a potential relationship between shift/night shift work and the risk of stroke.

METHODS

We searched PubMed, Embase, the Cochrane Library and Web of science databases for eligible studies from inception to January 19, 2024. We followed the statement in the Preferred Reporting Items for Systematic Evaluations and Meta-Analysis (PRISMA). STATA 14.0 software was used for meta-analysis.

RESULTS

A total of five studies involving 700,742 subjects were included in this meta-analysis. We found that shift/night workers had a 1.08 times higher risk of stroke than non-shift/night workers (RR: 1.08; 95 % CI: 1.05-1.10; P < 0.001).

CONCLUSION

Shift/night work may be a risk factor for stroke. More objective prospective studies are needed to further support this result.

摘要

背景

轮班/夜间工作与中风风险之间的关联没有充分的证据支持。

目的

本研究旨在获得轮班/夜班工作与中风风险之间潜在关联的证据。

方法

我们从建库至 2024 年 1 月 19 日在 PubMed、Embase、Cochrane 图书馆和 Web of science 数据库中搜索合格的研究。我们遵循系统评价和荟萃分析的首选报告项目(PRISMA)中的说明。使用 STATA 14.0 软件进行荟萃分析。

结果

这项荟萃分析共纳入了五项涉及 700742 名受试者的研究。我们发现,轮班/夜间工作者发生中风的风险比非轮班/夜间工作者高 1.08 倍(RR:1.08;95%CI:1.05-1.10;P<0.001)。

结论

轮班/夜间工作可能是中风的一个危险因素。需要更多客观的前瞻性研究来进一步支持这一结果。

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