Danisco Animal Nutrition and Health (IFF), 2342 BH, Oegstgeest, The Netherlands.
Danisco Animal Nutrition and Health (IFF), 2342 BH, Oegstgeest, The Netherlands.
Poult Sci. 2024 Jul;103(7):103857. doi: 10.1016/j.psj.2024.103857. Epub 2024 May 15.
Pressure to reduce the use of antibiotics in the poultry industry has intensified research on alternative solutions to support intestinal health, including but not limited to direct fed microbials (DFM). Heat stress is known to impact intestinal health and function. The aim of this study was to determine efficacy of a water applied DFM product on broiler performance during the summer period. One of two treatments were randomly allocated to 12 replicate floor pens each: a control treatment and a treatment provided daily with a dual strain DFM comprised of Lactobacillus acidophilus AG01 and Bifidobacterium animalis AG02 at 1 × 10 CFU/bird/d. Each pen contained 20 Ross 308 broilers. All birds were fed the same three-phased wheat- and soybean meal-based diets. Body weight, feed intake, feed conversion ratio, and mortality were measured at d 0, 10, 24, 35, and 42. Due to natural extreme external temperature conditions, all birds were subject to heat stress during the end of the grower phase up to and including the finisher phase. Temperature was on average 5°C higher compared to industry recommendation. No significant differences were found in growth performance between the control and DFM treatment, yet BW at d 42 in both treatments was reduced by 19% compared to the breed standard. The DFM treatment significantly reduced mortality among the birds. Overall mortality from d 1 to d 35 was reduced from 4.58% to 0.42% (P = 0.023) and overall mortality from d 1 to d 42 was reduced from 5.83 to 0.83% (P = 0.027). This was driven by the difference in heat-stress related mortality in the finisher phase from d 25 to d 42, where mortality reached only 0.44% in the DFM treatment versus 2.88% in the unsupplemented control treatment. Post-mortem analysis confirmed heat-stress related hypoxia. In conclusion, the dual strain DFM may have provided improved (intestinal) homeostasis and barrier function allowing increased resilience to heat stress in broilers.
为了减少家禽业中抗生素的使用，人们加紧研究替代解决方案来支持肠道健康，包括但不限于直接饲喂微生物（DFM）。众所周知，热应激会影响肠道健康和功能。本研究旨在确定在夏季期间，一种水应用 DFM 产品对肉鸡性能的功效。将两种处理中的一种随机分配到 12 个重复的地板笼中：对照组和每天提供由嗜酸乳杆菌 AG01 和动物双歧杆菌 AG02 组成的双重菌株 DFM 的处理组，剂量为 1×10 CFU/只/天。每个笼中含有 20 只罗斯 308 肉鸡。所有鸡都喂食相同的三阶段小麦和豆粕基础日粮。在 d 0、10、24、35 和 42 时测量体重、采食量、饲料转化率和死亡率。由于极端的外部温度条件，所有鸡在生长期结束时直至育肥期都受到热应激。温度平均比行业建议高 5°C。对照组和 DFM 处理组在生长性能方面没有发现显著差异，但两个处理组的 d 42 体重比品种标准降低了 19%。DFM 处理显著降低了鸡的死亡率。从 d 1 到 d 35 的总死亡率从 4.58%降至 0.42%（P=0.023），从 d 1 到 d 42 的总死亡率从 5.83%降至 0.83%（P=0.027）。这是由于育肥期从 d 25 到 d 42 期间热应激相关死亡率的差异所致，DFM 处理组的死亡率仅为 0.44%，而未补充对照组的死亡率为 2.88%。剖检分析证实与热应激相关的低氧血症。总之，双重菌株 DFM 可能为肉鸡提供了改善的（肠道）稳态和屏障功能，从而提高了对热应激的抵抗力。
