Silvia N Susan, Velrajan Mahalakshmi
Department of Microbiology, Madras Christian College, Chennai, Tamil Nadu, India.
Curr Diabetes Rev. 2025;21(6):1-11. doi: 10.2174/0115733998287694240514110935.
Diabetic foot wounds and infections pose a significant and evolving challenge in diabetes care. Diabetic wound healing has become a major global concern for a very long time. Continuous research has been conducted to increase the healing process in diabetic ulcers to the rate of amputation. Wound healing is prolonged in diabetic patients due to various conditions, such as high glucose levels, neuropathy, poor blood circulation, and prolonged inflammation around the limbs, which causes the healing to be delayed compared to normal patients. Understanding the complexity of chronic foot wounds and the management and proper treatment would lead to a decrease in the risk of amputation. The medical team all over the world is constantly researching to lower the risk. This review paper offers a compelling journey through the multifaceted world of diabetic foot wounds and infections. It underscores the urgency of understanding classification, tackling multidrug resistance, and harnessing microbial insights to revolutionize the treatment and management of diabetic foot complications. Furthermore, it unveils state-of-the-art diagnostics, heralding a brighter future in the battle against this debilitating complication of diabetes.
糖尿病足伤口和感染在糖尿病护理中构成了重大且不断演变的挑战。长期以来，糖尿病伤口愈合一直是全球主要关注的问题。人们持续开展研究，以提高糖尿病溃疡的愈合速度，降低截肢率。由于高血糖水平、神经病变、血液循环不良以及肢体周围长期炎症等多种因素，糖尿病患者的伤口愈合时间延长，与正常患者相比愈合延迟。了解慢性足部伤口的复杂性以及管理和恰当治疗方法，将降低截肢风险。世界各地的医疗团队一直在不断研究以降低该风险。这篇综述文章带领我们踏上了一段穿越糖尿病足伤口和感染多面世界的引人入胜之旅。它强调了理解分类、应对多重耐药性以及利用微生物见解来彻底改变糖尿病足并发症治疗和管理的紧迫性。此外，它还揭示了先进的诊断方法，预示着在对抗这种使人衰弱的糖尿病并发症的战斗中有着更光明的未来。
