Manchester Centre for Health Psychology, Division of Psychology and Mental Health, School of Health Sciences, University of Manchester, Manchester, UK.
The Prevent Breast Cancer Research Unit, The Nightingale Centre, Manchester University NHS Foundation Trust, Manchester, UK.
J Hum Nutr Diet. 2024 Aug;37(4):995-1006. doi: 10.1111/jhn.13313. Epub 2024 May 27.
The Manchester Intermittent versus Daily Diet App Study (MIDDAS) tested the feasibility and potential efficacy of two remotely delivered low-energy diet (LED) programmes (800 kcal/day) to support weight loss and remission of type 2 diabetes: continuous [CLED] (8 weeks of daily LED) and intermittent [ILED] (2 days of LED/week for 28 weeks). Understanding participant experiences can help us to understand the acceptability of LED programmes to people with type 2 diabetes, informing future programme development and implementation.
Twenty participants (10 CLED; 10 ILED) took part in interviews conducted at the end of the active weight loss phase (CLED week 12, ILED week 28). Interviews were transcribed and analysed thematically using the template analysis approach, with an a priori focus on acceptability. Four themes are presented: prospective acceptability, intervention coherence and perceived effectiveness, opportunity costs and self-efficacy.
Both remotely supported CLED and ILED interventions appeared acceptable to participants. CLED participants found the rapid initial weight loss phase comparatively easy and highly motivating but expressed more concerns around weight maintenance. ILED participants found the more gradual weight loss initially frustrating but expressed greater confidence in their longer-term adherence. The importance of continued individualised support from healthcare professionals was emphasised, and evidence of weight loss and improvement in other medical markers through monitoring via the mobile phone app was useful.
Different approaches to remotely delivered LEDs appear acceptable; therefore asking patients which approach may be more acceptable to them may be a useful way to offer individualised and tailored support.
曼彻斯特间断性与每日饮食 App 研究（MIDDAS）测试了两种远程提供的低能量饮食（LED）方案（每天 800 千卡）支持体重减轻和 2 型糖尿病缓解的可行性和潜在疗效：连续[CLED]（每天 LED 治疗 8 周）和间断性[ILED]（每周 2 天 LED 治疗，共 28 周）。了解参与者的体验可以帮助我们了解 LED 方案对 2 型糖尿病患者的可接受性，为未来的方案开发和实施提供信息。
20 名参与者（10 名 CLED；10 名 ILED）在主动减肥阶段结束时（CLED 第 12 周，ILED 第 28 周）接受了访谈。访谈记录被转录，并使用模板分析方法进行主题分析，预先关注可接受性。呈现了四个主题：预期的可接受性、干预的连贯性和感知的有效性、机会成本和自我效能。
远程支持的 CLED 和 ILED 干预对参与者来说似乎都是可以接受的。CLED 参与者发现快速的初始体重减轻阶段相对容易且非常有动力，但对体重维持表示了更多的担忧。ILED 参与者发现最初的体重减轻较为缓慢而感到沮丧，但对长期坚持的信心更大。强调了继续从医疗保健专业人员那里获得个性化支持的重要性，通过手机应用程序进行监测来证明体重减轻和其他医疗指标的改善是有用的。
不同的远程 LED 方法似乎都是可以接受的；因此，询问患者哪种方法对他们更可接受可能是提供个性化和定制支持的一种有用方法。
