Lollar Matthew J, Kim Elizabeth, Stern David L, Pool John E
Laboratory of Genetics, University of Wisconsin - Madison, Madison, WI, 53705, USA.
Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147 USA.
bioRxiv. 2025 Feb 24:2024.05.14.594231. doi: 10.1101/2024.05.14.594231.
The courtship song of has long served as an excellent model system for studies of animal communication and differences in courtship song have been demonstrated among populations and between species. Here, we report that flies of African and European origin, which diverged approximately 13,000 years ago, show significant genetic differentiation in the use of slow versus fast pulse song. Using a combination of quantitative trait mapping and population genetic analysis we detected a single strong QTL underlying this trait and we identified candidate genes that may contribute to the evolution of this trait. Song trait variation between parental strains of our recombinant inbred panel enabled detection of genomic intervals associated with six additional song traits, some of which include known courtship-related genes. These findings improve the prospects for further genetic insights into the evolution of reproductive behavior and the biology underlying courtship song.
长期以来，[某种生物]的求偶歌一直是研究动物交流的优秀模型系统，并且已经证明不同种群之间以及不同物种之间的求偶歌存在差异。在这里，我们报告说，大约在13000年前分化的非洲和欧洲起源的果蝇，在使用慢脉冲歌与快脉冲歌方面表现出显著的遗传分化。通过结合数量性状定位和群体遗传分析，我们检测到了一个单一的强数量性状基因座，该基因座是这一性状的基础，并且我们鉴定出了可能有助于这一性状进化的候选基因。我们重组近交系面板的亲本菌株之间的歌声性状变异，使得能够检测到与另外六个歌声性状相关的基因组区间，其中一些包括已知的与求偶相关的基因。这些发现改善了进一步从遗传学角度深入了解生殖行为进化以及求偶歌背后生物学机制的前景。
