Horton Katie N, Gassmann Walter
Division of Plant Science and Technology, Bond Life Sciences Center, and Interdisciplinary Plant Group, University of Missouri, Columbia, MO, United States.
Front Plant Sci. 2024 May 10;15:1400659. doi: 10.3389/fpls.2024.1400659. eCollection 2024.
Phytopathogenic microbes use secreted effector proteins to increase their virulence . If these effectors or the results of their activity are detected by the plant cell, the plant will mount an immune response which applies evolutionary pressure by reducing growth and success of the pathogen. Bacterial effector proteins in the AvrRps4 family (AvrRps4, HopK1, and XopO) have commonly been used as tools to investigate plant immune components. At the same time, the functions of this family of effectors have yet to be fully characterized. In this minireview we summarize current knowledge about the AvrRps4 effector family with emphasis on properties of the proteins themselves. We hypothesize that the HopK1 C-terminus and the AvrRps4 C-terminus, though unrelated in sequence and structure, are broadly related in functions that counteract plant defense responses.
植物病原微生物利用分泌的效应蛋白来增强其毒力。如果这些效应蛋白或其活性结果被植物细胞检测到，植物就会启动免疫反应，通过降低病原体的生长和繁殖来施加进化压力。AvrRps4家族的细菌效应蛋白（AvrRps4、HopK1和XopO）通常被用作研究植物免疫成分的工具。与此同时，该效应蛋白家族的功能尚未完全明确。在这篇小型综述中，我们总结了关于AvrRps4效应蛋白家族的现有知识，重点是蛋白质本身的特性。我们推测，HopK1的C末端和AvrRps4的C末端虽然在序列和结构上不相关，但在对抗植物防御反应的功能上具有广泛的相关性。
