Hong Juyeon, Seong Daewoon, Kang Dongwan, Kim Hyunmo, Jang Jeong Hun, Jeon Mansik, Kim Jeehyun
School of Electronic and Electrical Engineering, College of IT Engineering, Kyungpook National University, 80, Daehak-ro, Buk-gu, Daegu 41566, South Korea.
Department of Otolaryngology, School of Medicine, Ajou University, 206, World cup-ro, Yeongtong-gu, Suwon 16499, South Korea.
APL Bioeng. 2024 May 23;8(2):026113. doi: 10.1063/5.0203582. eCollection 2024 Jun.
Novel hearable technology is securely and comfortably positioned within the ear canal minimizing inaccuracies caused by accessory movements during activities. Despite extensive research on hearable technologies within the outer ear, there is a lack of research in the field of vascular imaging and quantitative analysis in the outer ear , which is one of the crucial factors to select the appropriate sensor position. Therefore, in this paper, we introduced optical coherence tomography angiography (OCTA)-based qualitative and quantitative analyses to visualize the inner vasculature of the outer ear to acquire vascular maps for microvascular assessments . By generating maximum amplitude projection images from three-dimensional blood vascular volume, we identified variations of blood vessel signal caused by the different biological characteristics and curvature of the ear among individuals. The performance of micro-vascular mapping using the proposed method was validated through the comparison and analysis of individual vascular parameters using extracted 20 vascular-related variables. In addition, we extracted pulsatile blood flow signals, demonstrating its potential to provide photoplethysmographic signals and ear blood maps simultaneously. Therefore, our proposed OCTA-based method for ear vascular mapping successfully provides quantitative information about ear vasculature, which is potentially used for determining the position of system-on-chip sensors for health monitoring in hearable devices.
新型可听技术安全舒适地置于耳道内,可最大程度减少活动期间辅助运动引起的误差。尽管对外耳内的可听技术进行了广泛研究,但外耳血管成像和定量分析领域仍缺乏研究,而这是选择合适传感器位置的关键因素之一。因此,在本文中,我们引入了基于光学相干断层扫描血管造影(OCTA)的定性和定量分析,以可视化外耳的内部血管系统,获取用于微血管评估的血管图谱。通过从三维血管容积生成最大振幅投影图像,我们识别了个体之间因耳朵不同生物学特征和曲率导致的血管信号变化。使用提取的20个与血管相关的变量,通过对个体血管参数的比较和分析,验证了使用所提出方法进行微血管映射的性能。此外,我们提取了搏动血流信号,证明了其同时提供光电容积脉搏波信号和耳部血流图谱的潜力。因此,我们提出的基于OCTA的耳部血管映射方法成功提供了有关耳部血管系统的定量信息,这可能用于确定可听设备中用于健康监测的片上系统传感器的位置。