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碱性条件下3-酮糖苷在340nm处吸收的分子基础

Molecular Basis of Absorption at 340 nm of 3-Ketoglucosides under Alkaline Conditions.

作者信息

Kitaoka Motomitsu, Takano Ayu, Takahashi Mei, Yamakawa Yoshiki, Fushinobu Shinya, Yoshida Nobuyuki

机构信息

1 Faculty of Agriculture, Niigata University.

2 Department of Biotechnology, The University of Tokyo.

出版信息

J Appl Glycosci (1999). 2024 Apr 20;71(1):9-13. doi: 10.5458/jag.jag.JAG-2023_0014. eCollection 2024.

DOI:10.5458/jag.jag.JAG-2023_0014
PMID:38799412
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11116085/
Abstract

Transient absorption at 340 nm under alkaline conditions has long been used to detect the presence of 3-keto--glycosides without understanding the molecular basis of the absorbance. The time course of for the alkaline treatment of 3-ketolevoglucosan, an intramolecular 3-keto--glycoside, was investigated to identify the three products generated through alkaline treatment. By comparing the spectra of these compounds under neutral and alkaline conditions, we identified 1,5-anhydro-D--hex-1-en-3-ulose (2-hydroxy-3-keto-D-glucal) as being the compound responsible for the absorption.

摘要

长期以来，在碱性条件下340nm处的瞬态吸收一直被用于检测3-酮基-β-糖苷的存在，但并不了解吸光度的分子基础。对分子内3-酮基-β-糖苷3-酮基左旋葡聚糖进行碱性处理的时间进程进行了研究，以鉴定通过碱性处理产生的三种产物。通过比较这些化合物在中性和碱性条件下的光谱，我们确定1,5-脱水-D-阿拉伯-己-1-烯-3-酮糖（2-羟基-3-酮基-D-葡糖醛）是负责吸收的化合物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0169/11116085/e4a5befb74a3/JAG-71-009-g07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0169/11116085/55141c49dc89/JAG-71-009-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0169/11116085/dcd06e26b017/JAG-71-009-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0169/11116085/768c3b8eae17/JAG-71-009-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0169/11116085/aacb6f5c62f3/JAG-71-009-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0169/11116085/098387afe042/JAG-71-009-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0169/11116085/8da1b983c3e2/JAG-71-009-g06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0169/11116085/e4a5befb74a3/JAG-71-009-g07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0169/11116085/55141c49dc89/JAG-71-009-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0169/11116085/dcd06e26b017/JAG-71-009-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0169/11116085/768c3b8eae17/JAG-71-009-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0169/11116085/aacb6f5c62f3/JAG-71-009-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0169/11116085/098387afe042/JAG-71-009-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0169/11116085/8da1b983c3e2/JAG-71-009-g06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0169/11116085/e4a5befb74a3/JAG-71-009-g07.jpg

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