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阻塞性睡眠呼吸暂停患者体重指数与呼吸暂停低通气指数或最低血氧饱和度水平之间的相关性

Correlation Between Body Mass Index and Apnea-Hypopnea Index or Nadir Oxygen Saturation Levels in Patients With Obstructive Sleep Apnea.

作者信息

Uzair Ahmed, Waseem Muhammad, Bin Shahid Aun, Bhatti Nauman I, Arshad Muhammad, Ishaq Asher, Sajawal Muhammad, Toor Zoha, Ahmad Osama

机构信息

Pulmonary Medicine, Sahiwal Medical College & Allied Teaching Hospital, Sahiwal, PAK.

Internal Medicine, Sahiwal Medical College & Allied Teaching Hospital, Sahiwal, PAK.

出版信息

Cureus. 2024 Apr 26;16(4):e59066. doi: 10.7759/cureus.59066. eCollection 2024 Apr.

Abstract

BACKGROUND

Apnea-hypopnea index (AHI) and nadir oxygen saturation (SpO2) are the indexes used to measure the severity of obstructive sleep apnea (OSA). Obesity, measured by body mass index (BMI), is one of the main contributing factors to the onset and severity of OSA in patients. This study was conducted to find the association between BMI and OSA severity indexes, mainly AHI and nadir SpO2 levels.

METHODS

Polysomnography reports of patients with diagnosed OSA in a teaching hospital were retrospectively reviewed. BMI, AHI, and nadir SpO2 levels were recorded from the sleep study reports of the patients. Spearman's Rho test was applied to find the correlation between BMI and AHI/nadir Spo2 levels.

RESULTS

A total of 167 patients were included in the study, comprising 83 males and 84 females. The Mann-Whitney U test was utilized to investigate the association between BMI and gender and age groups. The analysis revealed a significant difference in BMI between males and females, with females having a higher BMI. However, there was no significant difference in BMI among individuals in the early middle and late middle age groups. Spearman's Rho test was employed to explore the correlation between BMI and AHI/nadir SpO2 levels. The results indicated no significant correlation between BMI and AHI (= .122) or nadir SpO2 levels (= .239).

CONCLUSION

Contrary to common belief, BMI was not linked to the severity of OSA. It implies that several other factors, independent of BMI, play a role in the disease progression and severity.

摘要

背景

呼吸暂停低通气指数(AHI)和最低血氧饱和度(SpO2)是用于衡量阻塞性睡眠呼吸暂停(OSA)严重程度的指标。通过体重指数(BMI)衡量的肥胖是患者OSA发病和严重程度的主要促成因素之一。本研究旨在探讨BMI与OSA严重程度指标之间的关联,主要是AHI和最低SpO2水平。

方法

回顾性分析一家教学医院确诊为OSA患者的多导睡眠图报告。从患者的睡眠研究报告中记录BMI、AHI和最低SpO2水平。应用Spearman等级相关检验来确定BMI与AHI/最低SpO2水平之间的相关性。

结果

本研究共纳入167例患者,其中男性83例,女性84例。采用Mann-Whitney U检验来研究BMI与性别和年龄组之间的关联。分析显示男性和女性之间的BMI存在显著差异,女性的BMI更高。然而,在中年早期、中期和晚期个体的BMI之间没有显著差异。采用Spearman等级相关检验来探讨BMI与AHI/最低SpO2水平之间的相关性。结果表明BMI与AHI(=0.122)或最低SpO2水平(=0.239)之间无显著相关性。

结论

与普遍看法相反,BMI与OSA的严重程度无关。这意味着一些独立于BMI的其他因素在疾病进展和严重程度中起作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b6b/11128192/2b202aa6310d/cureus-0016-00000059066-i01.jpg

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