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阻塞性睡眠呼吸暂停与肥胖:对公共卫生的影响。

Obstructive Sleep Apnea and Obesity: Implications for Public Health.

作者信息

Jehan Shazia, Zizi Ferdinand, Pandi-Perumal Seithikurippu R, Wall Steven, Auguste Evan, Myers Alyson K, Jean-Louis Girardin, McFarlane Samy I

机构信息

Department of Population Health, Center for Healthful Behavior Change, USA.

Somnogen Canada Inc, Canada.

出版信息

Sleep Med Disord. 2017;1(4). Epub 2017 Dec 12.

Abstract

Obstructive sleep apnea (OSA) is a global disease with a rising incidence along with its comorbidities, especially with metabolic syndrome. One of the main components contributing to sleep apnea is obesity; as well as diabetes mellitus type 2 (T2DM), hypercholesterolemia, and hypertension. OSA is a condition that requires management and the disease can be treated by using CPAP therapy. The awareness of this global issue is rising, and health care systems are providing preventive measures, diagnosis and the treatment options. The major preventable risk factors to decrease obesity are the awareness of lifestyle modification (eating behaviors, smoking, drinking alcohol, etc.) and understanding the importance of exercise. If these lifestyle modifications are widely applied, then not only will the consequences of obesity and sleep apnea be reduced, but also the incidence of cardiovascular disease will decrease greatly. Public awareness of the importance of weight loss by lifestyle modification or bariatric surgery to improve the quality of life is needed. These preventive actions, screening measures, and treatment strategies for obesity and OSA can significantly reduce the incidence of obesity, as well as OSA and the related comorbidities such as cardiovascular disease, atherosclerosis, and depression. Finally, health care costs will also be reduced.

摘要

阻塞性睡眠呼吸暂停(OSA)是一种全球性疾病,其发病率及其合并症,尤其是与代谢综合征相关的发病率呈上升趋势。导致睡眠呼吸暂停的主要因素之一是肥胖;还有2型糖尿病(T2DM)、高胆固醇血症和高血压。OSA是一种需要管理的疾病,可通过持续气道正压通气(CPAP)疗法进行治疗。对这一全球性问题的认识正在提高,医疗保健系统正在提供预防措施、诊断和治疗选择。降低肥胖的主要可预防风险因素是对生活方式改变(饮食行为、吸烟、饮酒等)的认识以及对运动重要性的理解。如果广泛应用这些生活方式的改变,那么不仅肥胖和睡眠呼吸暂停的后果会降低,而且心血管疾病的发病率也会大幅下降。需要公众认识到通过生活方式改变或减肥手术来减轻体重对改善生活质量的重要性。这些针对肥胖和OSA的预防行动、筛查措施和治疗策略可以显著降低肥胖、OSA以及相关合并症(如心血管疾病、动脉粥样硬化和抑郁症)的发病率。最后,医疗保健成本也将降低。

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