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及时手术切除可使睾丸鞘膜恶性间皮瘤及腹膜后复发患者获得长期缓解。

Timely Surgical Resection Achieved Prolonged Remission in Patients With Malignant Mesothelioma of the Tunica Vaginalis Testis and Retroperitoneal Recurrence.

作者信息

Radovanovic Milan, Kojic Uros, Zubelic Aleksa, Jakulic Djordje, Filipovic Zoran

机构信息

Clinic of Urology, University Clinical Centre of Serbia, Clinic of Urology, Belgrade, SRB.

Urology, University Hospital Medical Center Bezanijska Kosa, Belgrade, SRB.

出版信息

Cureus. 2024 Apr 26;16(4):e59052. doi: 10.7759/cureus.59052. eCollection 2024 Apr.

DOI:10.7759/cureus.59052
PMID:38800313
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11128090/
Abstract

Malignant mesothelioma of the tunica vaginalis testis (MMTVT) is a rare tumor of the testicular sheath. More than 50% of cases initially present as recurrent hydrocele, but there have also been documented cases with hematocele, inguinal hernia, or epididymitis. Due to the non-specific symptoms and signs of the disease, it is almost always diagnosed intra- or postoperatively. The lack of standardized therapy protocols, as well as the lack of evidence supporting systemic chemotherapy, have fueled arguments in favor of the necessity of retroperitoneal lymph node dissection (RPLND) in the treatment of the disease, especially in the case of lymph node metastasis. We present a case of MMTVT achieving prolonged remission after timely and extensive surgical treatment.

摘要

睾丸鞘膜恶性间皮瘤(MMTVT)是一种罕见的睾丸鞘膜肿瘤。超过50%的病例最初表现为复发性鞘膜积液,但也有文献记载的病例表现为血囊肿、腹股沟疝或附睾炎。由于该疾病的症状和体征不具有特异性,几乎总是在术中或术后才得以诊断。缺乏标准化的治疗方案,以及缺乏支持全身化疗的证据,引发了关于在该疾病治疗中进行腹膜后淋巴结清扫术(RPLND)必要性的争论,尤其是在发生淋巴结转移的情况下。我们报告一例MMTVT患者,在接受及时且广泛的手术治疗后实现了长期缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/998b/11128090/e234d93a0c8d/cureus-0016-00000059052-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/998b/11128090/5881489c9ee2/cureus-0016-00000059052-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/998b/11128090/8eff61cfb7a7/cureus-0016-00000059052-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/998b/11128090/39e127d28e3d/cureus-0016-00000059052-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/998b/11128090/486b817126f0/cureus-0016-00000059052-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/998b/11128090/e234d93a0c8d/cureus-0016-00000059052-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/998b/11128090/5881489c9ee2/cureus-0016-00000059052-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/998b/11128090/8eff61cfb7a7/cureus-0016-00000059052-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/998b/11128090/39e127d28e3d/cureus-0016-00000059052-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/998b/11128090/486b817126f0/cureus-0016-00000059052-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/998b/11128090/e234d93a0c8d/cureus-0016-00000059052-i05.jpg

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本文引用的文献

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A rare malignant mesothelioma of the tunica vaginalis testis: A case report.睾丸鞘膜罕见恶性间皮瘤:一例报告。
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Role of robot-assisted retroperitoneal lymph node dissection in malignant mesothelioma of the tunica vaginalis: case series and review of the literature.机器人辅助腹膜后淋巴结清扫术在鞘膜恶性间皮瘤中的作用:病例系列及文献综述
Can J Urol. 2019 Jun;26(3):9752-9757.
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Testicular Mesothelioma: An Analysis of Epidemiology, Patient Outcomes, and Prognostic Factors.睾丸间皮瘤:流行病学、患者预后及预后因素分析
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Malignant Mesothelioma of the Tunica Vaginalis Testis: Outcomes Following Surgical Management Beyond Radical Orchiectomy.睾丸鞘膜恶性间皮瘤:根治性睾丸切除术后手术治疗的结果
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