Mizushima Y
Department of Internal Medicine, St. Marianna University, Kawasaki, Japan.
Drugs Exp Clin Res. 1985;11(9):595-600.
Lipid microsphere preparations of corticosteroid, non-steroid anti-inflammatory drugs and prostaglandin E1 (PGE1) all showed more potent activity than the free drugs. Lipo-PGE1 in particular was significantly more active than free PGE1 at about one-tenth the dose of free PGE1. A large mass of data obtained in studies of liposomes suggest many applications for the lipid microsphere, which is considered to be a very promising carrier in drug delivery systems.