Yamaguchi T, Mizushima Y
Department of Pharmaceutics, Taisho Pharmaceutical Co., Ltd., Saitama, Japan.
Crit Rev Ther Drug Carrier Syst. 1994;11(4):215-29.
Lipid microsphere (LM) preparations of corticosteroid, nonsteroid, anti-inflammatory drugs and prostaglandins all showed more potent activity than free drugs. The LM, with a diameter of 0.2 microns, were drug carriers prepared from soybean oil and lecithin, with the drug being incorporated within the LM. This study suggests that the LM is a very promising carrier in a drug delivery system. Future trends in this field are outlined, followed by a discussion of physicochemical properties in the evaluation of novel emulsion delivery systems.
