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Lipid microspheres for drug delivery from the pharmaceutical viewpoint.

作者信息

Yamaguchi T, Mizushima Y

机构信息

Department of Pharmaceutics, Taisho Pharmaceutical Co., Ltd., Saitama, Japan.

出版信息

Crit Rev Ther Drug Carrier Syst. 1994;11(4):215-29.

PMID:7664347
Abstract

Lipid microsphere (LM) preparations of corticosteroid, nonsteroid, anti-inflammatory drugs and prostaglandins all showed more potent activity than free drugs. The LM, with a diameter of 0.2 microns, were drug carriers prepared from soybean oil and lecithin, with the drug being incorporated within the LM. This study suggests that the LM is a very promising carrier in a drug delivery system. Future trends in this field are outlined, followed by a discussion of physicochemical properties in the evaluation of novel emulsion delivery systems.

摘要

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