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急性阑尾炎继发菌血症:一例病例报告并文献复习

bacteremia secondary to acute appendicitis: a case report with review of literature.

作者信息

Sasi Sreethish, Nair Arun Prabhakaran, Doiphode Sanjay, Gutti Tejeswi Shashidhar, Kolleri Jouhar, Al-Maslamani Muna

机构信息

Infectious Diseases Division, Department of Internal Medicine, Hamad Medical Corporation, Doha 3050, Qatar.

Infectious Diseases Division, Department of Internal Medicine, Communicable Diseases Center, Hamad Medical Corporation, Doha 3050, Qatar.

出版信息

J Surg Case Rep. 2024 May 24;2024(5):rjae328. doi: 10.1093/jscr/rjae328. eCollection 2024 May.

DOI:10.1093/jscr/rjae328
PMID:38800504
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11126336/
Abstract

This report describes a rare instance of bacteremia secondary to acute appendicitis in a young man. Initially presenting with symptoms typical of appendicitis, he was diagnosed through clinical examination, laboratory tests, and computed tomography imaging, which confirmed an inflamed appendix with sealed perforation and abscess. , a Gram-negative anaerobe commonly found in the human gut, was identified as the causative agent through blood culture. The patient underwent successful laparoscopic appendectomy and was treated with intravenous amoxicillin-clavulanate, leading to a full recovery. This case highlights the potential of to act as an opportunistic pathogen in the context of intra-abdominal inflammation. It underscores the diagnostic challenges posed by , and the efficacy of advanced diagnostic tools like matrix-assisted laser desorption/ionization-time of flight mass spectrometry in identifying such rare infections.

摘要

本报告描述了一名年轻男性因急性阑尾炎继发菌血症的罕见病例。他最初表现出阑尾炎的典型症状,通过临床检查、实验室检查和计算机断层扫描成像确诊,这些检查证实阑尾发炎并有封闭性穿孔和脓肿。通过血培养鉴定出一种常见于人体肠道的革兰氏阴性厌氧菌为病原体。患者接受了成功的腹腔镜阑尾切除术,并接受静脉注射阿莫西林 - 克拉维酸治疗,最终完全康复。该病例突出了[病原体名称未给出]在腹腔内炎症情况下作为机会性病原体的可能性。它强调了[病原体名称未给出]带来的诊断挑战,以及基质辅助激光解吸/电离飞行时间质谱等先进诊断工具在识别此类罕见感染方面的有效性。

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本文引用的文献

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2
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Anaerobe. 2022 Dec;78:102663. doi: 10.1016/j.anaerobe.2022.102663. Epub 2022 Oct 11.
3
Gut Microbiota and Short Chain Fatty Acids: Implications in Glucose Homeostasis.
肠道微生物群和短链脂肪酸:在葡萄糖稳态中的作用。
Int J Mol Sci. 2022 Jan 20;23(3):1105. doi: 10.3390/ijms23031105.
4
Novel Strain and Its Outer Membrane Vesicles Exert Immunoregulatory Effects .新型菌株及其外膜囊泡发挥免疫调节作用。
Front Microbiol. 2020 Nov 12;11:575455. doi: 10.3389/fmicb.2020.575455. eCollection 2020.
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Whole-Cell MALDI-TOF MS Versus 16S rRNA Gene Analysis for Identification and Dereplication of Recurrent Bacterial Isolates.全细胞基质辅助激光解吸电离飞行时间质谱与16S rRNA基因分析用于复发性细菌分离株的鉴定和去重复化
Front Microbiol. 2018 Jun 19;9:1294. doi: 10.3389/fmicb.2018.01294. eCollection 2018.
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Complete genome sequence of Odoribacter splanchnicus type strain (1651/6).内脏气味杆菌模式菌株(1651/6)的全基因组序列
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