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利用无刺蜂四角切叶蜂的花粉提取物绿色合成银纳米颗粒。

Green synthesis of silver nanoparticle using pollen extract from Tetragonisca angustula a stingless bee.

作者信息

Santos Ana Carolina Costa, Batista Gabriela Carvalho, Cerqueira Rafaela Cavalcante, Lisboa Mariana Gonçalves, Correa Joberth Lee, Rodrigues Tamiris Sabrina, da Silva Murillo Néia Thomaz, Bittar Vinícius Prado, Malta Serena Mares, Dos Santos Natalia Carine Lima, Espindola Foued Salmen, Bonetti Ana Maria, Ueira-Vieira Carlos

机构信息

Laboratory of Genetics, Institute of Biotechnology, Federal University of Uberlândia, Uberlandia, Brazil.

Laboratory of Nanobiotechnology, Institute of Biotechnology, Federal University of Uberlândia, Uberlandia, Brazil.

出版信息

Discov Nano. 2024 May 27;19(1):92. doi: 10.1186/s11671-024-04038-0.

Abstract

This study explores the green synthesis of silver nanoparticles (AgNPs) using a methanolic extract of fermented pollen from Tetragonisca angustula, a species of stingless bees. The AgNPs exhibit spherical morphology, low charge values, and suspension stability, with their unique composition attributed to elements from the pollen extract. Antioxidant assays show comparable activity between the pollen extract and AgNPs, emphasizing the retention of antioxidant effects. The synthesized AgNPs demonstrate antimicrobial activity against multidrug-resistant bacteria, highlighting their potential in combating bacterial resistance. The AgNPs exhibit no toxic effects on Drosophila melanogaster and even enhance the hatching rate of eggs. The study underscores the innovative use of stingless bee pollen extract in green synthesis, offering insights into the varied applications of AgNPs in biomedicine.

摘要

本研究探索了使用无刺蜂四角切叶蜂发酵花粉的甲醇提取物绿色合成银纳米颗粒(AgNPs)。AgNPs呈现球形形态、低电荷值和悬浮稳定性,其独特的组成归因于花粉提取物中的元素。抗氧化试验表明花粉提取物和AgNPs之间具有相当的活性,强调了抗氧化作用的保留。合成的AgNPs对多重耐药细菌表现出抗菌活性,突出了它们在对抗细菌耐药性方面的潜力。AgNPs对黑腹果蝇没有毒性作用,甚至提高了卵的孵化率。该研究强调了无刺蜂花粉提取物在绿色合成中的创新应用,为AgNPs在生物医学中的各种应用提供了见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0587/11130103/89d9134372f8/11671_2024_4038_Fig1_HTML.jpg

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