Yael Goverover, PhD, OTR/L, FAOTA, is Professor, Department of Occupational Therapy, New York University, New York, NY;
Saumya Sharan, MS, OTR/L, is Student, Department of Occupational Therapy, New York University, New York, NY.
Am J Occup Ther. 2024 Jul 1;78(4). doi: 10.5014/ajot.2024.050468.
This pilot study evaluates a remote strategy-based intervention for individuals with multiple sclerosis who experience everyday memory impairments. The intervention can potentially inform cognitive rehabilitation for this population.
To investigate the feasibility and efficacy of an intervention (TELE-Self-GEN) to determine whether it can alleviate everyday memory impairments of individuals with multiple sclerosis.
Pretest-posttest.
Community.
Ten adults with multiple sclerosis.
Six synchronous treatment sessions were delivered online via Zoom. The treatment protocol embedded a memory strategy (self-generated learning) within a metacognitive framework, including self-awareness and self-management strategies. The treatment emphasizes when and how self-generation should be used.
Measurements assessed feasibility and participants' satisfaction with the intervention and its delivery method, as well as memory, everyday memory, and functional performance.
Participants expressed high satisfaction with the virtual treatment, highlighting its convenience as a key factor. Treatment resulted in improvements in memory performance, perceived memory ability in daily life, and functional performance.
Results provide initial proof of concept in the utilization of a remotely delivered, strategy-based treatment approach to improve memory performance and functional abilities. The pilot data support a larger randomized clinical trial of the TELE-self-GEN. Plain-Language Summary: The results of this pilot study highlight the promising potential of TELE-self-GEN for people with multiple sclerosis (MS), who face memory challenges every day. This remotely delivered, strategy-based occupational therapy treatment approach, TELE-self-GEN, has the potential to significantly improve functional memory. The study participants reported improvements in their memory performance, perceived memory ability in daily life, and functional performance. These encouraging results serve as a foundation for more extensive clinical trials using TELE-self-GEN for people with MS.
重要性：本试点研究评估了一种针对多发性硬化症患者的远程基于策略的干预措施，这些患者在日常生活中存在记忆障碍。该干预措施可能为该人群的认知康复提供信息。
目的：研究一种干预措施（TELE-Self-GEN）的可行性和疗效，以确定它是否可以减轻多发性硬化症患者的日常记忆障碍。
设计：预测试-后测试。
地点：社区。
参与者：十名多发性硬化症患者。
干预：通过 Zoom 在线进行六次同步治疗课程。治疗方案将记忆策略（自我生成学习）嵌入元认知框架内，包括自我意识和自我管理策略。该治疗强调何时以及如何使用自我生成。
结果：测量评估了干预措施及其交付方法的可行性和参与者的满意度，以及记忆、日常生活记忆和功能表现。
结果：参与者对虚拟治疗表示高度满意，强调其便利性是一个关键因素。治疗导致记忆表现、日常生活中感知的记忆能力和功能表现的改善。
结论和相关性：结果提供了使用远程提供的基于策略的治疗方法来改善记忆表现和功能能力的初步概念验证。试点数据支持 TELE-self-GEN 的更大规模随机临床试验。
白话摘要：这项试点研究的结果突显了 TELE-self-GEN 对多发性硬化症 (MS) 患者的巨大潜力，这些患者每天都面临记忆挑战。这种远程提供的、基于策略的职业治疗方法 TELE-self-GEN 具有显著改善功能性记忆的潜力。研究参与者报告说，他们的记忆表现、日常生活中感知的记忆能力和功能表现都有所改善。这些令人鼓舞的结果为使用 TELE-self-GEN 对多发性硬化症患者进行更广泛的临床试验奠定了基础。
