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增强多发性硬化症患者的日常记忆及参与度:一项基于元认知策略干预的试点研究。

Enhancing everyday memory and participation in multiple sclerosis: A pilot study of a metacognitive strategy-based intervention.

作者信息

Goverover Yael, Rosenfeld Meirav, DeLuca John, Toglia Joan

机构信息

Department of Occupational Therapy, New York University, New York, NY, USA; Kessler Foundation, East Hanover, NJ, USA.

Department of Occupational Therapy, New York University, New York, NY, USA.

出版信息

Mult Scler J Exp Transl Clin. 2025 Apr 15;11(2):20552173251333383. doi: 10.1177/20552173251333383. eCollection 2025 Apr-Jun.

Abstract

BACKGROUND

Cognitive dysfunction in individuals with multiple sclerosis (MS) is associated with limitations in daily activities and restricted participation. Existing interventions for cognitive dysfunction often show inconsistent transfer to everyday activities and typically require frequent clinic visits, which can be challenging for patients with MS due to mobility issues. To address this barrier, we developed a telehealth-based cognitive intervention that is based on metacognitive strategy training.

OBJECTIVE

Examine the feasibility and impact of a telehealth-based cognitive intervention on activity and participation in persons with MS.

METHODS

Ten participants with MS were included in a remote six-week, 12 sessions cognitive treatment program. The treatment emphasized self-generation and metacognitive strategies to enhance cognitive function. Participants' cognitive abilities were evaluated at baseline (Time 1), midtreatment (Time 2), and posttreatment (Time 3).

RESULTS

Participants demonstrated improved memory, self-awareness, strategy use, and functional status. Participants reported enhanced confidence and better focus and found the remote program engaging and applicable to daily life, reporting increased preparedness for learning.

CONCLUSION

Results provide preliminary proof-of-concept data suggesting that telehealth-based cognitive intervention is well accepted by patients and may improve cognitive functions in persons with MS. These data support the need for a larger trial for this intervention.

摘要

背景

多发性硬化症(MS)患者的认知功能障碍与日常活动受限和参与度降低有关。现有的针对认知功能障碍的干预措施往往在向日常活动的转化方面表现不一致,并且通常需要频繁就诊,这对于患有MS的患者来说可能具有挑战性,因为他们存在行动不便的问题。为了克服这一障碍,我们开发了一种基于远程医疗的认知干预措施,该措施基于元认知策略训练。

目的

研究基于远程医疗的认知干预对MS患者的活动和参与度的可行性及影响。

方法

10名MS患者参加了一个为期六周、共12节课程的远程认知治疗项目。该治疗强调自我生成和元认知策略以增强认知功能。在基线期(时间1)、治疗中期(时间2)和治疗后期(时间3)对参与者的认知能力进行评估。

结果

参与者的记忆力、自我意识、策略运用和功能状态均有所改善。参与者报告称自信心增强、注意力更集中,并且发现远程项目有趣且适用于日常生活,还表示对学习的准备更充分。

结论

结果提供了初步的概念验证数据,表明基于远程医疗的认知干预受到患者的广泛接受,并且可能改善MS患者的认知功能。这些数据支持对该干预措施进行更大规模试验的必要性。

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