Department of Pathology and Laboratory Medicine, the University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX, USA
Department of Pathology and Laboratory Medicine, the University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX, USA.
Ann Clin Lab Sci. 2024 Mar;54(2):246-250.
Von Willebrand disease (VWD) is the most common inherited bleeding disorder. It is primarily attributed to malfunctioning or deficient Von Willebrand factor (VWF). Thromboelastography (TEG) has emerged as a valuable tool for assessing coagulation dynamics and guiding transfusion therapy in bleeding patients. Given this, we present a case study of a 23-year-old pregnant female with a past medical history of type 2B VWD, wherein TEG was employed to optimize disease screening and therapy monitoring while minimizing costs and preventing complications associated with low platelet counts. This case underscores the potential utility of TEG in enhancing the care of VWD patients, particularly in unique critical settings such as pregnancy.
血管性血友病(VWD)是最常见的遗传性出血性疾病。它主要归因于血管性血友病因子(VWF)的功能障碍或缺乏。血栓弹性描记术(TEG)已成为评估出血患者凝血动力学和指导输血治疗的有价值工具。有鉴于此,我们报告了一例 23 岁孕妇的病例,该患者既往有 2B 型血管性血友病病史,其中使用 TEG 来优化疾病筛查和治疗监测,同时最大限度地降低与血小板计数低相关的成本和并发症。该病例突出了 TEG 在增强 VWD 患者护理中的潜在效用,特别是在妊娠等独特的危急情况下。