Department of Obstetrics and Gynecology, Changhua Christian Hospital, Changhua, Taiwan.
In Vitro Fertilization Laboratory, Department of Obstetrics and Gynecology, Changhua Christian Hospital, Changhua, Taiwan.
Taiwan J Obstet Gynecol. 2024 May;63(3):409-413. doi: 10.1016/j.tjog.2023.12.002.
Monochorionic-triamniotic (MCTA) triplet pregnancies following artificial reproductive technologies are uncommon. We report a case in which one of two transferred embryos differentiated into an MCTA triplet. This study aimed to investigate the potential factors contributing to MCTA triplet pregnancy.
A 39-year-old woman underwent her second frozen embryo transfer with hatching blastocysts, which resulted in the detection of an MCTA triplet on ultrasonography. She delivered by cesarean section at 32 weeks of gestation, resulting in the birth of three live male infants. Her medical history and in vitro fertilization treatment were reviewed to identify potential causes.
The etiology of MCTA triplet pregnancy remains multifactorial. In the presented case, prolonged in vitro culture to the blastocyst stage and inner cell mass splitting were potential contributing factors. Further research is needed to fully understand the complexity of MCTA triplet pregnancy.
人工生殖技术导致的单绒毛膜三羊膜囊(MCTA)三胎妊娠较为罕见。我们报告了一例由两枚移植胚胎中的一枚分化为 MCTA 三胎妊娠的病例。本研究旨在探讨导致 MCTA 三胎妊娠的潜在因素。
一名 39 岁女性接受了第二次冷冻胚胎移植,移植的是孵化囊胚,超声检查发现 MCTA 三胎妊娠。她在 32 周时行剖宫产术分娩,产下 3 名活男婴。回顾她的病史和体外受精治疗,以确定潜在的病因。
MCTA 三胎妊娠的病因仍具有多因素性。在本病例中,延长体外培养至囊胚阶段和内细胞团分裂可能是潜在的促成因素。需要进一步的研究来全面了解 MCTA 三胎妊娠的复杂性。