一个用于识别转运核糖核酸（tRNA）基因的微型计算机程序。

A microcomputer program for the identification of tRNA genes.

作者信息

Paolella G, Russo T

机构信息

Istituto di Scienze Biochimiche, II Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli, Italy.

出版信息

Comput Appl Biosci. 1985 Sep;1(3):149-51. doi: 10.1093/bioinformatics/1.3.149.

DOI:10.1093/bioinformatics/1.3.149

PMID:3880339

Abstract

A microcomputer program which locates tRNA genes within long DNA sequences is described. The search is performed either by identifying tRNA-like secondary structures or by locating eukaryotic RNA polymerase III promoter consensus sequences. The program is also useful in finding inverted repeats allowing the formation of stem-loop secondary structures in tRNA. The program has been developed in BASIC and 6502 Assembler and runs on the Apple II plus and IIe microcomputers. The execution is quite fast; all the operations are carried out in 1-90 s, depending on the required task and on the sequence length.

摘要

本文描述了一种用于在长DNA序列中定位tRNA基因的微机程序。该搜索可通过识别类似tRNA的二级结构或定位真核RNA聚合酶III启动子共有序列来进行。该程序在寻找允许tRNA形成茎环二级结构的反向重复序列方面也很有用。该程序是用BASIC语言和6502汇编语言开发的，可在Apple II plus和IIe微机上运行。执行速度相当快；所有操作在1 - 90秒内完成，具体取决于所需任务和序列长度。