儿童脑白质营养不良的磁共振成像

Magnetic resonance imaging in leukodystrophies of childhood.

作者信息

Young R S, Osbakken M D, Alger P M, Ramer J C, Weidner W A, Daigh J D

机构信息

Department of Pediatrics, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey 17033.

出版信息

Pediatr Neurol. 1985 Jan-Feb;1(1):15-9. doi: 10.1016/0887-8994(85)90003-7.

DOI:10.1016/0887-8994(85)90003-7

PMID:3880385

Abstract

Magnetic resonance imaging (MRI) is particularly valuable in the diagnosis of childhood brain disorders with abnormal myelination because MRI may identify lesions not always seen with x-ray CT scans. We report the clinical and magnetic resonance findings of six children with leukodystrophy. T2 weighted (spin-echo) images disclosed striking asymmetric involvement of cerebral white matter, particularly in periventricular white matter and visual radiations. Calculated T1 values were significantly elevated in the children with leukodystrophy.

摘要

磁共振成像（MRI）在诊断伴有髓鞘形成异常的儿童脑部疾病方面具有特殊价值，因为MRI能够识别出X线计算机断层扫描（CT扫描）不一定能发现的病变。我们报告了6例脑白质营养不良患儿的临床和磁共振检查结果。T2加权（自旋回波）图像显示脑白质有明显的不对称受累，尤其是脑室周围白质和视辐射。脑白质营养不良患儿的计算T1值显著升高。