Ment L R, Scott D T, Ehrenkranz R A, Duncan C C
Yale University School of Medicine, Department of Pediatrics, New Haven, CT.
Pediatr Neurol. 1985 May-Jun;1(3):164-8. doi: 10.1016/0887-8994(85)90058-x.
During a recent 36-month interval, all neonates of less than or equal to 1250 gram birth weight who were admitted to our Newborn Special Care Unit and survived the first 36 postnatal hours underwent either computed tomography or echoencephalography or both for the assessment of neonatal germinal matrix hemorrhage and intraventricular hemorrhage. Seventy of the 164 long-term surviving infants experienced neonatal germinal matrix and/or intraventricular hemorrhage (GMH/IVH Group), whereas 94 infants had studies that were negative (Non-hemorrhage Group). Serial neurodevelopmental assessments were performed on 142 (87%) of the 164 long-term surviving infants; these assessments included the Bayley Scales of Infant Development at 3, 6, 12, and 18 months (corrected age) and the Stanford-Binet and Peabody Picture Vocabulary examinations at 30 months (corrected age). At 30 months (corrected age), the incidence of major neurologic abnormalities was extremely low in both the GMH/IVH and the Non-hemorrhage groups. In addition, although there were few survivors of the more severe grades of intraventricular hemorrhage, we could detect no difference between the developmental scores of the GMH/IVH and the Non-hemorrhage Group infants.
在最近的36个月期间，所有出生体重小于或等于1250克、入住我们新生儿特别护理病房并在出生后最初36小时存活下来的新生儿，均接受了计算机断层扫描或脑回波描记术或两者检查，以评估新生儿生发基质出血和脑室内出血情况。164名长期存活婴儿中，70名经历了新生儿生发基质和/或脑室内出血（GMH/IVH组），而94名婴儿的检查结果为阴性（非出血组）。对164名长期存活婴儿中的142名（87%）进行了系列神经发育评估；这些评估包括在3、6、12和18个月（矫正年龄）时进行的贝利婴儿发育量表，以及在30个月（矫正年龄）时进行的斯坦福-比奈智力量表和皮博迪图片词汇测试。在30个月（矫正年龄）时，GMH/IVH组和非出血组的严重神经异常发生率都极低。此外，虽然脑室内出血较严重等级的幸存者很少，但我们未发现GMH/IVH组和非出血组婴儿的发育评分有差异。
