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加拿大癌症幸存者使用大麻作为助眠剂相关因素的横断面调查。

A Cross Sectional Survey of Factors Related to Cannabis Use as a Sleep Aid Among Canadian Cancer Survivors.

机构信息

Department of Psychology, Faculty of Science, Memorial University, St. John's, NL, Canada.

Pharmacy, Beatrice Hunter Cancer Research Institute, Halifax, NS, Canada.

出版信息

Behav Sleep Med. 2024 Sep-Oct;22(5):754-769. doi: 10.1080/15402002.2024.2361015. Epub 2024 May 28.

Abstract

OBJECTIVES

Poor sleep is a common side effect of cancer. Cannabis is increasingly used to manage cancer treatment-related symptoms, including sleep. This study investigated factors related to cannabis use for sleep among Canadian cancer survivors.

METHOD

Adult Canadian cancer survivors ( = 940) were recruited via the Angus Reid Institute and completed an online, cross-sectional survey. Univariate and multiple binomial logistic regression models identified factors associated with cannabis use for sleep.

RESULTS

Of the participants (M = 64.5 yrs; Women = 51.1%; White = 92.9%), 25.1% ( = 236) currently use cannabis for sleep. Participants were at greater odds of using cannabis for sleep if they identified as a gender other than man or woman (AOR = 11.132), were diagnosed with multiple medical conditions (2:AOR = 1.988; 3+:AOR = 1.902), two psychological conditions (AOR = 2.171), multiple sleep disorders (AOR = 2.338), insomnia (AOR = 1.942), bone (AOR = 6.535), gastrointestinal (AOR = 4.307), genitourinary (AOR = 2.586), hematological (AOR = 4.739), or an unlisted cancer (AOR = 3.470), received hormone therapy only (AOR = 3.054), drink heavily (AOR = 2.748), or had mild insomnia (AOR = 1.828). Older participants (AOR=.972) and those with sleep apnea were less likely to use cannabis for sleep (AOR=.560).

CONCLUSION

Given its prevalence, research is needed to understand how factors associated with cannabis use as a sleep aid among Canadian cancer survivors may influence its use and effectiveness and whether these factors are barriers to accessing evidence-based treatments.

摘要

目的

睡眠质量差是癌症的常见副作用。大麻被越来越多地用于治疗癌症治疗相关症状,包括睡眠。本研究调查了加拿大癌症幸存者使用大麻改善睡眠的相关因素。

方法

通过 Angus Reid 研究所招募成年加拿大癌症幸存者(n=940),并完成了一项在线横断面调查。单变量和多变量二项逻辑回归模型确定了与使用大麻改善睡眠相关的因素。

结果

在 940 名参与者中(平均年龄 64.5 岁;女性 51.1%;白人 92.9%),25.1%(n=236)目前使用大麻改善睡眠。如果参与者的性别为非男性或女性(AOR=11.132)、被诊断患有多种疾病(2:AOR=1.988;3+:AOR=1.902)、两种心理疾病(AOR=2.171)、多种睡眠障碍(AOR=2.338)、失眠(AOR=1.942)、骨骼(AOR=6.535)、胃肠道(AOR=4.307)、泌尿生殖系统(AOR=2.586)、血液学(AOR=4.739)或未列出的癌症(AOR=3.470)、仅接受激素治疗(AOR=3.054)、大量饮酒(AOR=2.748)或有轻度失眠(AOR=1.828),那么他们使用大麻改善睡眠的可能性更高。年龄较大的参与者(AOR=.972)和患有睡眠呼吸暂停的参与者使用大麻改善睡眠的可能性较低(AOR=.560)。

结论

鉴于其普遍性,需要开展研究以了解与加拿大癌症幸存者使用大麻作为助眠剂相关的因素如何影响其使用和有效性,以及这些因素是否成为获得循证治疗的障碍。

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