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经颅磁刺激作为长期和深空任务行为及神经心理风险的应对措施。

Transcranial magnetic stimulation as a countermeasure for behavioral and neuropsychological risks of long-duration and deep-space missions.

作者信息

Faerman Afik, Buchanan Derrick M, Williams Nolan R

机构信息

Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA.

出版信息

NPJ Microgravity. 2024 May 28;10(1):58. doi: 10.1038/s41526-024-00401-8.

DOI:10.1038/s41526-024-00401-8
PMID:38806522
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11133369/
Abstract

Long-duration spaceflight missions are on the rise. However, recent literature suggests that prolonged and deep-space exposure is likely to introduce increased risks for brain health and consequent detriments to performance and well-being. Given up-to-date evidence, we argue that transcranial magnetic stimulation (TMS) is a promising solution for mitigating behavioral and neurocognitive risks associated with long-duration and deep-space missions. We provide support from recent Earth-based applications of TMS and review several advantages it holds over current treatment approaches. Lastly, we highlight some of the needs in the process of applying such technology to the spaceflight environment.

摘要

长期太空飞行任务正在增加。然而,最近的文献表明,长时间的深空暴露可能会增加大脑健康风险,并进而损害性能和幸福感。鉴于最新证据,我们认为经颅磁刺激(TMS)是减轻与长期和深空任务相关的行为和神经认知风险的一种有前景的解决方案。我们提供了TMS在近期地面应用中的支持,并回顾了它相对于当前治疗方法的几个优势。最后,我们强调了将此类技术应用于太空飞行环境过程中的一些需求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11d1/11133369/d79f9bb82f79/41526_2024_401_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11d1/11133369/d79f9bb82f79/41526_2024_401_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11d1/11133369/d79f9bb82f79/41526_2024_401_Fig1_HTML.jpg

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本文引用的文献

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Sustained Efficacy of Stanford Neuromodulation Therapy (SNT) in Open-Label Repeated Treatment.斯坦福神经调节疗法(SNT)在开放标签重复治疗中的持续疗效。
Am J Psychiatry. 2024 Jan 1;181(1):71-73. doi: 10.1176/appi.ajp.20230113.
2
Neuropsychological considerations for long-duration deep spaceflight.长期深空飞行的神经心理学考量
Front Physiol. 2023 May 19;14:1146096. doi: 10.3389/fphys.2023.1146096. eCollection 2023.
3
The effect of long-term spaceflight on drug potency and the risk of medication failure.长期太空飞行对药物效力及用药失败风险的影响。
NPJ Microgravity. 2023 May 5;9(1):35. doi: 10.1038/s41526-023-00271-6.
4
Optimizing transcranial magnetic stimulation for spaceflight applications.优化用于航天应用的经颅磁刺激。
NPJ Microgravity. 2023 Mar 28;9(1):26. doi: 10.1038/s41526-023-00249-4.
5
Repetitive transcranial magnetic stimulation in primary sleep disorders.重复经颅磁刺激治疗原发性睡眠障碍。
Sleep Med Rev. 2023 Feb;67:101735. doi: 10.1016/j.smrv.2022.101735. Epub 2022 Dec 8.
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Repetitive Transcranial Magnetic Stimulation for Generalized Anxiety Disorder: A Systematic Literature Review and Meta-Analysis.重复经颅磁刺激治疗广泛性焦虑障碍的系统文献回顾和荟萃分析。
Int J Neuropsychopharmacol. 2022 Feb 11;25(2):144-146. doi: 10.1093/ijnp/pyab077.
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Stanford Neuromodulation Therapy (SNT): A Double-Blind Randomized Controlled Trial.斯坦福神经调节疗法(SNT):一项双盲随机对照试验。
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