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脂肪神经细胞瘤:中枢神经系统的罕见肿瘤

Liponeurocytoma: Rare Neoplasm of the Central Nervous System.

作者信息

Sokol Zachary, Parsells Peter, Madineni Ravichandra

机构信息

Lewis Katz School of Medicine, Temple University, Philadelphia, USA.

Neurosurgery, Main Line Health, Bryn Mawr, USA.

出版信息

Cureus. 2024 Apr 28;16(4):e59221. doi: 10.7759/cureus.59221. eCollection 2024 Apr.

DOI:10.7759/cureus.59221
PMID:38807804
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11132662/
Abstract

In this case report, we characterize an instance of diagnosis, treatment, characteristics, and outcomes of a patient with a liponeurocytoma, a rare WHO grade II brain tumor first described in 1978. This tumor has been described with a wide array of radiographic, microscopic, and histologic features, and there remains no consensus regarding the role of radiation therapy. Most patients have favorable outcomes after surgical resection. Here we present the case of a 46-year-old female who underwent suboccipital craniectomy for resection of a cerebellar mass, which was diagnosed as liponeurocytoma on final pathology. The patient experienced resolution of symptoms and is neurologically intact two years after resection of the tumor.

摘要

在本病例报告中,我们描述了一例脂肪神经细胞瘤患者的诊断、治疗、特征及预后情况。脂肪神经细胞瘤是一种罕见的WHO二级脑肿瘤,于1978年首次被描述。该肿瘤具有多种影像学、显微镜下和组织学特征,关于放射治疗的作用尚无共识。大多数患者在手术切除后预后良好。在此,我们报告一例46岁女性患者,她接受了枕下颅骨切除术以切除小脑肿块,最终病理诊断为脂肪神经细胞瘤。患者症状消失,肿瘤切除两年后神经功能完好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11132662/6ea96a406780/cureus-0016-00000059221-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11132662/cbccc10dc4aa/cureus-0016-00000059221-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11132662/547a09752ea2/cureus-0016-00000059221-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11132662/f4932cda1480/cureus-0016-00000059221-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11132662/6ea96a406780/cureus-0016-00000059221-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11132662/cbccc10dc4aa/cureus-0016-00000059221-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11132662/547a09752ea2/cureus-0016-00000059221-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11132662/f4932cda1480/cureus-0016-00000059221-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a84/11132662/6ea96a406780/cureus-0016-00000059221-i04.jpg

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本文引用的文献

1
Glioneuronal Tumor With Features of Ganglioglioma and Neurocytoma Arising in the Fourth Ventricle: A Report of 2 Unusual Cases and a Review of Infratentorial Gangliogliomas.第四脑室具有神经节细胞瘤和神经细胞瘤特征的胶质神经元肿瘤:2 例罕见病例报告及小脑幕下神经节细胞瘤的复习。
J Neuropathol Exp Neurol. 2019 Sep 1;78(9):780-787. doi: 10.1093/jnen/nlz060.
2
Liponeurocytoma: Systematic Review of a Rare Entity.脂肪神经细胞瘤:一种罕见实体的系统评价
World Neurosurg. 2018 Dec;120:214-233. doi: 10.1016/j.wneu.2018.09.001. Epub 2018 Sep 8.
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Liponeurocytoma of the Cerebellopontine Angle.
小脑脑桥角脂肪神经细胞瘤
World Neurosurg. 2018 Apr;112:18-24. doi: 10.1016/j.wneu.2018.01.012. Epub 2018 Jan 8.
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The clinicopathological features of liponeurocytoma.脂肪神经细胞瘤的临床病理特征
Brain Tumor Pathol. 2017 Jan;34(1):28-35. doi: 10.1007/s10014-017-0279-7. Epub 2017 Feb 24.
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Cerebellar liponeurocytoma.小脑脂肪神经细胞瘤
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