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秋水仙碱治疗肩肱关节骨关节炎:一例报告

Colchicine Therapy for Glenohumeral Osteoarthritis: A Case Report.

作者信息

Sadik Oman, Tahir Sophia, Sahibzada Anum, Iguh Chinenye, Ezenwa Virginia, Bhavanam Sravani

机构信息

Family Medicine, Jackson Park Hospital, Chicago, USA.

Internal Medicine, Windsor University School of Medicine, Cayon, KNA.

出版信息

Cureus. 2024 Apr 27;16(4):e59181. doi: 10.7759/cureus.59181. eCollection 2024 Apr.

DOI:10.7759/cureus.59181
PMID:38807809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11130563/
Abstract

Osteoarthritis management primarily focuses on targeting pain. Conventional modalities for pain management include acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs), and intra-articular corticosteroid injections. However, these approaches may provide minimal pain relief and can be contraindicated for some patients, highlighting the ongoing need for alternative pain management. Colchicine, commonly used in the management of gout, has emerged as a potential option for pain management in osteoarthritis. There are implications of colchicine use for knee and hand osteoarthritis but remains inconclusive. In this context, we present a case of a 68-year-old diabetic woman with glenohumeral osteoarthritis and associated right shoulder pain. Due to minimal pain relief from previous treatments, the patient was given a combination trial of colchicine and acetaminophen for three months. After completion of this treatment, the patient experienced significant pain relief and improved functionality. The aim of this case is to highlight the efficacy of colchicine as a possible treatment option for managing shoulder pain in osteoarthritis.

摘要

骨关节炎的治疗主要侧重于缓解疼痛。传统的疼痛管理方法包括对乙酰氨基酚、非甾体抗炎药(NSAIDs)和关节内注射皮质类固醇。然而,这些方法可能只能提供轻微的疼痛缓解,并且对某些患者可能是禁忌的,这凸显了对替代疼痛管理方法的持续需求。秋水仙碱常用于痛风的治疗,已成为骨关节炎疼痛管理的一种潜在选择。秋水仙碱用于膝关节和手部骨关节炎有一定意义,但仍无定论。在此背景下,我们报告一例68岁患有盂肱关节骨关节炎并伴有右肩疼痛的糖尿病女性病例。由于先前治疗的疼痛缓解效果不佳,该患者接受了秋水仙碱和对乙酰氨基酚联合治疗三个月的试验。完成该治疗后,患者疼痛明显缓解,功能得到改善。本病例的目的是强调秋水仙碱作为治疗骨关节炎肩部疼痛的一种可能治疗选择的疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72a2/11130563/bd8befc575d1/cureus-0016-00000059181-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72a2/11130563/9251b3c481e0/cureus-0016-00000059181-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72a2/11130563/bd8befc575d1/cureus-0016-00000059181-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72a2/11130563/9251b3c481e0/cureus-0016-00000059181-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72a2/11130563/bd8befc575d1/cureus-0016-00000059181-i02.jpg

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本文引用的文献

1
Colchicine twice a day for hand osteoarthritis (COLOR): a double-blind, randomised, placebo-controlled trial.秋水仙碱每天两次治疗手骨关节炎(COLOR):一项双盲、随机、安慰剂对照试验。
Lancet Rheumatol. 2023 May;5(5):e254-e262. doi: 10.1016/S2665-9913(23)00065-6. Epub 2023 Apr 4.
2
Osteoarthritis: New Insight on Its Pathophysiology.骨关节炎:对其病理生理学的新见解
J Clin Med. 2022 Oct 12;11(20):6013. doi: 10.3390/jcm11206013.
3
Efficacy and safety of colchicine for the treatment of osteoarthritis: a systematic review and meta-analysis of intervention trials.
秋水仙碱治疗骨关节炎的疗效和安全性:干预试验的系统评价和荟萃分析。
Clin Rheumatol. 2023 Mar;42(3):889-902. doi: 10.1007/s10067-022-06402-w. Epub 2022 Oct 12.
4
The Involvement of Neutrophils in the Pathophysiology and Treatment of Osteoarthritis.中性粒细胞在骨关节炎病理生理学及治疗中的作用
Biomedicines. 2022 Jul 6;10(7):1604. doi: 10.3390/biomedicines10071604.
5
Shoulder Osteoarthritis.肩关节骨关节炎。
Radiol Clin North Am. 2022 Jul;60(4):593-603. doi: 10.1016/j.rcl.2022.03.003.
6
Therapeutic potential of colchicine in cardiovascular medicine: a pharmacological review.秋水仙碱在心血管医学中的治疗潜力:药理学评价。
Acta Pharmacol Sin. 2022 Sep;43(9):2173-2190. doi: 10.1038/s41401-021-00835-w. Epub 2022 Jan 19.
7
Imaging and Biochemical Markers for Osteoarthritis.骨关节炎的影像学和生化标志物
Diagnostics (Basel). 2021 Jul 2;11(7):1205. doi: 10.3390/diagnostics11071205.
8
Diagnosis and Treatment of Hip and Knee Osteoarthritis: A Review.髋关节和膝关节骨关节炎的诊断与治疗:综述
JAMA. 2021 Feb 9;325(6):568-578. doi: 10.1001/jama.2020.22171.
9
Matrix Metalloproteinases and Their Inhibitors and Proteoglycan 4 in Patients Undergoing Total Joint Arthroplasty.全关节置换术患者体内的基质金属蛋白酶及其抑制剂与蛋白聚糖4
Clin Appl Thromb Hemost. 2019 Jan-Dec;25:1076029619828113. doi: 10.1177/1076029619828113.
10
A double-blind randomized controlled trial appraising the symptom-modifying effects of colchicine on osteoarthritis of the knee.一项评价秋水仙碱对膝关节骨关节炎症状改善作用的双盲随机对照试验。
Clin Exp Rheumatol. 2011 May-Jun;29(3):513-8. Epub 2011 Jun 29.