Durak Büşra, Gunduz Gurkan Canan, Özol Duygu, Saraç Sema
Department of Pulmonology, Hitit University Faculty of Medicine, Çorum, TUR.
Department of Pulmonology, Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, TUR.
Cureus. 2024 May 28;16(5):e61215. doi: 10.7759/cureus.61215. eCollection 2024 May.
Obstructive sleep apnea syndrome (OSAS) is a severe condition that is characterized by recurrent partial or complete breathing interruptions during sleep, leading to insulin resistance, microvascular complications, and cardiovascular complications. It is of great importance to know the impact of type 2 diabetes mellitus (DM), which is prevalent in the world and in our country, Turkey, leads to significant mortality and morbidity, significantly affects the quality of life, and requires continuous follow-up, on sleep in patients with OSAS and to raise awareness on this issue. In this study, we aimed to determine the effects of diabetes on sleep duration and sleep architecture in patients with OSAS and to investigate the relationship between OSAS severity and DM control.
Fifty diabetic and 42 non-diabetic patients diagnosed with OSAS at the Sleep Disorders Center of Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Turkey, between October 2022 and March 2023 were included in the study. Polysomnographic and biochemical parameters of the two groups were compared. The effect of OSAS severity and sleep architecture on diabetes control was investigated.
No significant difference was found between diabetic and non-diabetic patients in terms of total sleep duration, sleep efficiency, and sleep latency, whereas REM (rapid eye movement) latency was prolonged and REM sleep duration and percentage were significantly lower in diabetic patients. The severity of OSAS was found to be greater in diabetic patients and they spent significantly more time below 90% saturation during sleep. No correlation was found between the groups in the glycated hemoglobin (HbA1c) parameter, which we examined in terms of diabetes control, sleep architecture, and OSAS severity.
The presence of diabetes aggravates the severity of OSAS, prolongs the transition to REM sleep, and leads to a decrease in REM duration. Sleep is essential for both mental and physical well-being. In this regard, it is of utmost importance to examine diabetic patients for OSAS and to perform polysomnography in appropriate patients.
阻塞性睡眠呼吸暂停综合征（OSAS）是一种严重病症，其特征为睡眠期间反复出现部分或完全性呼吸中断，进而导致胰岛素抵抗、微血管并发症和心血管并发症。2型糖尿病（DM）在全球及我国土耳其普遍存在，导致显著的死亡率和发病率，严重影响生活质量且需要持续随访，了解其对OSAS患者睡眠的影响并提高对此问题的认识至关重要。在本研究中，我们旨在确定糖尿病对OSAS患者睡眠时间和睡眠结构的影响，并探究OSAS严重程度与DM控制之间的关系。
2022年10月至2023年3月期间，在土耳其伊斯坦布尔苏雷亚帕夏胸科疾病与胸外科培训和研究医院睡眠障碍中心被诊断为OSAS的50例糖尿病患者和42例非糖尿病患者纳入研究。比较两组的多导睡眠图和生化参数。研究OSAS严重程度和睡眠结构对糖尿病控制的影响。
糖尿病患者与非糖尿病患者在总睡眠时间、睡眠效率和睡眠潜伏期方面未发现显著差异，而糖尿病患者的快速眼动（REM）潜伏期延长，REM睡眠时间和百分比显著降低。发现糖尿病患者的OSAS严重程度更高，且他们在睡眠期间饱和度低于90%的时间明显更长。在糖化血红蛋白（HbA1c）参数方面，我们从糖尿病控制、睡眠结构和OSAS严重程度进行检查，未发现两组之间存在相关性。
糖尿病的存在会加重OSAS的严重程度，延长进入REM睡眠的过渡时间，并导致REM睡眠时间减少。睡眠对身心健康都至关重要。在这方面，对糖尿病患者进行OSAS检查并对合适的患者进行多导睡眠图检查至关重要。
