Suppr超能文献

中国的脑膜炎:一例报告。

meningitis in China: a case report.

机构信息

Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Department of Neurology, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

出版信息

Front Public Health. 2024 May 14;12:1369703. doi: 10.3389/fpubh.2024.1369703. eCollection 2024.

Abstract

INTRODUCTION

is one of the porcine pathogens that have recently emerged as a pathogen capable of causing zoonoses in some humans. Patients infected with can present with sepsis, meningitis, or arthritis. Compared to common pathogens, such as , , and , infections in humans have been reported only rarely.

METHODS

This case report described a 57-year-old man who presented with impaired consciousness and fever following several days of backache. He was a butcher who worked in an abattoir and had wounded his hands 2 weeks prior. The patient was dependent on alcohol for almost 40 years. was detected in the cerebrospinal fluid by metagenomic next-generation sequencing. Although he received adequate meropenem and low-dose steroid therapy, the patient suffered from bilateral sudden deafness after 5 days of the infection. The final diagnosis was meningitis and sepsis.

RESULTS

The patient survived with hearing loss in both ears and dizziness at the 60-day follow-up.

DISCUSSION

We reported a case of infection manifested as purulent meningitis and sepsis. Based on literature published worldwide, human meningitis shows an acute onset and rapid progression in the nervous system. Similar to bacterial meningitis, effective antibiotics, and low-dose steroids play important roles in the treatment of human meningitis.

摘要

简介

是最近出现的一种能够在某些人类中引起人畜共患病的猪病原体之一。感染的患者可能会出现败血症、脑膜炎或关节炎。与常见病原体如、和相比,人类感染的报道非常罕见。

方法

本病例报告描述了一名 57 岁男性,在背痛数天后出现意识障碍和发热。他是一名屠夫,在屠宰场工作,两周前手部受伤。该患者几乎 40 年来一直依赖酒精。通过宏基因组下一代测序在脑脊液中检测到。尽管他接受了足够的美罗培南和低剂量类固醇治疗,但在感染后 5 天,患者出现双侧突发性耳聋。最终诊断为化脓性脑膜炎和败血症。

结果

患者在 60 天随访时双耳听力丧失和头晕,但存活下来。

讨论

我们报告了一例感染表现为化脓性脑膜炎和败血症的病例。根据全球发表的文献,人类感染脑膜炎表现为神经系统急性发作和快速进展。与细菌性脑膜炎类似,有效的抗生素和低剂量类固醇在人类感染脑膜炎的治疗中发挥重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfed/11130402/2b9116dbc032/fpubh-12-1369703-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验