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Sex differences in Alzheimer's disease: an urgent research venue to follow.

作者信息

Jiménez-Herrera Raquel, Contreras Ana, Navarro-López Juan D, Jiménez-Díaz Lydia

机构信息

Neurophysiology & Behavior Lab, University of Castilla-La Mancha, School of Medicine of Ciudad Real, Ciudad Real, Spain.

出版信息

Neural Regen Res. 2024 Dec 1;19(12):2569-2570. doi: 10.4103/NRR.NRR-D-23-01971. Epub 2024 Mar 1.

DOI:10.4103/NRR.NRR-D-23-01971
PMID:38808985
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11168504/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3613/11168504/e7e73026c7f4/NRR-19-2569-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3613/11168504/e7e73026c7f4/NRR-19-2569-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3613/11168504/e7e73026c7f4/NRR-19-2569-g001.jpg

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本文引用的文献

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Systematic characterization of a non-transgenic Aβ amyloidosis model: synaptic plasticity and memory deficits in female and male mice.系统表征非转基因 Aβ 淀粉样变性模型：雌性和雄性小鼠的突触可塑性和记忆缺陷。
Biol Sex Differ. 2023 Sep 16;14(1):59. doi: 10.1186/s13293-023-00545-4.
2
Efficacy and safety of anti-amyloid-β monoclonal antibodies in current Alzheimer's disease phase III clinical trials: A systematic review and interactive web app-based meta-analysis.在当前阿尔茨海默病 III 期临床试验中抗淀粉样蛋白-β单克隆抗体的疗效和安全性：系统评价和基于交互式网络应用程序的荟萃分析。
Ageing Res Rev. 2023 Sep;90:102012. doi: 10.1016/j.arr.2023.102012. Epub 2023 Jul 7.
3
2023 Alzheimer's disease facts and figures.
2023 年阿尔茨海默病事实和数据。
Alzheimers Dement. 2023 Apr;19(4):1598-1695. doi: 10.1002/alz.13016. Epub 2023 Mar 14.
4
Sex Differences between Neuronal Loss and the Early Onset of Amyloid Deposits and Behavioral Consequences in 5xFAD Transgenic Mouse as a Model for Alzheimer's Disease.5xFAD 转基因小鼠模型中神经元丢失和淀粉样沉积的早期发生及行为后果的性别差异与阿尔茨海默病。
Cells. 2023 Mar 1;12(5):780. doi: 10.3390/cells12050780.
5
Transgenic Mouse Models of Alzheimer's Disease: An Integrative Analysis.阿尔茨海默病的转基因小鼠模型：综合分析。
Int J Mol Sci. 2022 May 12;23(10):5404. doi: 10.3390/ijms23105404.
6
Mitigating Effect of Estrogen in Alzheimer's Disease-Mimicking Cerebral Organoid.雌激素在模拟阿尔茨海默病的脑类器官中的缓解作用
Front Neurosci. 2022 Mar 24;16:816174. doi: 10.3389/fnins.2022.816174. eCollection 2022.
7
Dissecting the clinical heterogeneity of early-onset Alzheimer's disease.剖析早发性阿尔茨海默病的临床异质性。
Mol Psychiatry. 2022 Jun;27(6):2674-2688. doi: 10.1038/s41380-022-01531-9. Epub 2022 Apr 7.
8
Both male and female APPswe/PSEN1dE9 mice are impaired in spatial memory and cognitive flexibility at 9 months of age.雄性和雌性APPswe/PSEN1dE9小鼠在9个月大时空间记忆和认知灵活性均受损。
Neurobiol Aging. 2022 May;113:28-38. doi: 10.1016/j.neurobiolaging.2021.12.009. Epub 2022 Feb 12.
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