阿尔茨海默病中的性别差异：一个亟待跟进的研究领域。 - Suppr

Sex differences in Alzheimer's disease: an urgent research venue to follow.

作者信息

Jiménez-Herrera Raquel, Contreras Ana, Navarro-López Juan D, Jiménez-Díaz Lydia

机构信息

Neurophysiology & Behavior Lab, University of Castilla-La Mancha, School of Medicine of Ciudad Real, Ciudad Real, Spain.

出版信息

Neural Regen Res. 2024 Dec 1;19(12):2569-2570. doi: 10.4103/NRR.NRR-D-23-01971. Epub 2024 Mar 1.

DOI:10.4103/NRR.NRR-D-23-01971

PMID:38808985

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11168504/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3613/11168504/e7e73026c7f4/NRR-19-2569-g001.jpg

相似文献

Sex differences in Alzheimer's disease: an urgent research venue to follow.阿尔茨海默病中的性别差异：一个亟待跟进的研究领域。

Neural Regen Res. 2024 Dec 1;19(12):2569-2570. doi: 10.4103/NRR.NRR-D-23-01971. Epub 2024 Mar 1.

Sex-specific association of comorbid heart failure on mortality after Alzheimer's disease diagnosis in older adults aged 75 years and above: A health insurance claims data analysis in Japan.75岁及以上老年人阿尔茨海默病诊断后合并心力衰竭与死亡率的性别特异性关联：日本医疗保险理赔数据分析

J Alzheimers Dis. 2025 Feb;103(3):749-757. doi: 10.1177/13872877241305813. Epub 2025 Jan 10.

Front Aging Neurosci. 2025 Mar 4;17:1522434. doi: 10.3389/fnagi.2025.1522434. eCollection 2025.

Escape from X-chromosome inactivation and sex differences in Alzheimer's disease.从 X 染色体失活中逃脱以及阿尔茨海默病中的性别差异。

Rev Neurosci. 2024 Jan 1;35(3):341-354. doi: 10.1515/revneuro-2023-0108. Print 2024 Apr 25.

Relationship between sex biases in gene expression and sex biases in autism and Alzheimer's disease.基因表达中的性别偏见与自闭症和老年痴呆症中的性别偏见之间的关系。

Biol Sex Differ. 2024 Jun 7;15(1):47. doi: 10.1186/s13293-024-00622-2.

Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.阿尔茨海默病认知弹性的遗传结构中的性别差异。

Brain. 2022 Jul 29;145(7):2541-2554. doi: 10.1093/brain/awac177.

Sex differences for clinical correlates of substantia nigra neuron loss in people with Lewy body pathology.性别差异与路易体病患者黑质神经元丢失的临床相关因素。

Biol Sex Differ. 2024 Jan 19;15(1):8. doi: 10.1186/s13293-024-00583-6.

Race, polygenic risk and their association with incident dementia among older US adults.种族、多基因风险及其与美国老年成年人新发痴呆症的关联。

Brain Commun. 2022 Nov 30;4(6):fcac317. doi: 10.1093/braincomms/fcac317. eCollection 2022.

Sex Differences in Cognitive Decline in Subjects with High Likelihood of Mild Cognitive Impairment due to Alzheimer's disease.阿尔茨海默病导致轻度认知障碍可能性高的受试者中认知能力下降的性别差异。

Sci Rep. 2018 May 10;8(1):7490. doi: 10.1038/s41598-018-25377-w.

Risk and protective effects of the APOE gene towards Alzheimer's disease in the Kungsholmen project: variation by age and sex.在孔斯霍门项目中，APOE基因对阿尔茨海默病的风险及保护作用：随年龄和性别的变化

J Neurol Neurosurg Psychiatry. 2004 Jun;75(6):828-33. doi: 10.1136/jnnp.2003.021493.

本文引用的文献

Systematic characterization of a non-transgenic Aβ amyloidosis model: synaptic plasticity and memory deficits in female and male mice.系统表征非转基因 Aβ 淀粉样变性模型：雌性和雄性小鼠的突触可塑性和记忆缺陷。

Biol Sex Differ. 2023 Sep 16;14(1):59. doi: 10.1186/s13293-023-00545-4.

Efficacy and safety of anti-amyloid-β monoclonal antibodies in current Alzheimer's disease phase III clinical trials: A systematic review and interactive web app-based meta-analysis.在当前阿尔茨海默病 III 期临床试验中抗淀粉样蛋白-β单克隆抗体的疗效和安全性：系统评价和基于交互式网络应用程序的荟萃分析。

Ageing Res Rev. 2023 Sep;90:102012. doi: 10.1016/j.arr.2023.102012. Epub 2023 Jul 7.

2023 Alzheimer's disease facts and figures.2023 年阿尔茨海默病事实和数据。

Alzheimers Dement. 2023 Apr;19(4):1598-1695. doi: 10.1002/alz.13016. Epub 2023 Mar 14.

Sex Differences between Neuronal Loss and the Early Onset of Amyloid Deposits and Behavioral Consequences in 5xFAD Transgenic Mouse as a Model for Alzheimer's Disease.5xFAD 转基因小鼠模型中神经元丢失和淀粉样沉积的早期发生及行为后果的性别差异与阿尔茨海默病。

Cells. 2023 Mar 1;12(5):780. doi: 10.3390/cells12050780.

Transgenic Mouse Models of Alzheimer's Disease: An Integrative Analysis.阿尔茨海默病的转基因小鼠模型：综合分析。

Int J Mol Sci. 2022 May 12;23(10):5404. doi: 10.3390/ijms23105404.

Mitigating Effect of Estrogen in Alzheimer's Disease-Mimicking Cerebral Organoid.雌激素在模拟阿尔茨海默病的脑类器官中的缓解作用

Front Neurosci. 2022 Mar 24;16:816174. doi: 10.3389/fnins.2022.816174. eCollection 2022.

Dissecting the clinical heterogeneity of early-onset Alzheimer's disease.剖析早发性阿尔茨海默病的临床异质性。

Mol Psychiatry. 2022 Jun;27(6):2674-2688. doi: 10.1038/s41380-022-01531-9. Epub 2022 Apr 7.

Both male and female APPswe/PSEN1dE9 mice are impaired in spatial memory and cognitive flexibility at 9 months of age.雄性和雌性APPswe/PSEN1dE9小鼠在9个月大时空间记忆和认知灵活性均受损。

Neurobiol Aging. 2022 May;113:28-38. doi: 10.1016/j.neurobiolaging.2021.12.009. Epub 2022 Feb 12.

Past, present and future of therapeutic strategies against amyloid-β peptides in Alzheimer's disease: a systematic review.阿尔茨海默病中抗β淀粉样肽治疗策略的过去、现在和未来：系统评价。

Ageing Res Rev. 2021 Dec;72:101496. doi: 10.1016/j.arr.2021.101496. Epub 2021 Oct 21.

The informed road map to prevention of Alzheimer Disease: A call to arms.预防阿尔茨海默病的明智路线图：战斗的号角。

Mol Neurodegener. 2021 Jul 21;16(1):49. doi: 10.1186/s13024-021-00467-y.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

Sex differences in Alzheimer's disease: an urgent research venue to follow.

作者信息

机构信息

出版信息

相似文献

本文引用的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

相似文献

本文引用的文献